BioMediTech Institute and Faculty of Biomedical Sciences and Engineering, Tampere University of Technology, 33720 Tampere, Finland.
Sensors (Basel). 2018 May 24;18(6):1693. doi: 10.3390/s18061693.
Respiration rate (RR) provides useful information for assessing the status of a patient. We propose RR estimation based on photoplethysmography (PPG) because the blood perfusion dynamics are known to carry information on breathing, as respiration-induced modulations in the PPG signal. We studied the use of amplitude variability of transmittance mode finger PPG signal in RR estimation by comparing four time-frequency (TF) representation methods of the signal cascaded with a particle filter. The TF methods compared were short-time Fourier transform (STFT) and three types of synchrosqueezing methods. The public VORTAL database was used in this study. The results indicate that the advanced frequency reallocation methods based on synchrosqueezing approach may present improvement over linear methods, such as STFT. The best results were achieved using wavelet synchrosqueezing transform, having a mean absolute error and median error of 2.33 and 1.15 breaths per minute, respectively. Synchrosqueezing methods were generally more accurate than STFT on most of the subjects when particle filtering was applied. While TF analysis combined with particle filtering is a promising alternative for real-time estimation of RR, artefacts and non-respiration-related frequency components remain problematic and impose requirements for further studies in the areas of signal processing algorithms an PPG instrumentation.
呼吸频率 (RR) 为评估患者状况提供了有用的信息。我们提出基于光体积描记法 (PPG) 的 RR 估计,因为众所周知,PPG 信号中的血液灌注动力学携带有呼吸信息,如呼吸引起的 PPG 信号调制。我们通过比较信号与粒子滤波器级联的四种时频 (TF) 表示方法,研究了传输模式指 PPG 信号的幅度可变性在 RR 估计中的应用。比较的 TF 方法是短时傅里叶变换 (STFT) 和三种类型的同步挤压方法。本研究使用了公共的 VORTAL 数据库。结果表明,基于同步挤压方法的先进频率再分配方法可能优于线性方法,如 STFT。使用小波同步挤压变换获得了最佳结果,平均绝对误差和中位数误差分别为 2.33 和 1.15 次/分钟。在应用粒子滤波时,对于大多数受试者,同步挤压方法通常比 STFT 更准确。虽然 TF 分析结合粒子滤波是实时估计 RR 的一种很有前途的替代方法,但伪影和与呼吸无关的频率成分仍然是问题所在,并对信号处理算法和 PPG 仪器领域的进一步研究提出了要求。