Brim Hassan, Shahnazi Anahita, Nouraie Mehdi, Badurdeen Dilhana, Laiyemo Adeyinka O, Haidary Tahmineh, Afsari Ali, Ashktorab Hassan
Department of Medicine and Cancer Center, Howard University College of Medicine, Washington, DC, USA.
Department of Medicine, University of Pittsburgh, PA, USA.
Clin Med Insights Gastroenterol. 2018 May 18;11:1179552218778627. doi: 10.1177/1179552218778627. eCollection 2018.
Iron deficiency anemia (IDA) is a frequent disorder that is associated with many serious diseases. However, the findings of an evaluation of IDA-associated gastrointestinal disorders are lacking among African American patients.
To determine the most prevalent gastrointestinal lesions among African American patients with IDA especially in young men.
We reviewed medical records (n = 422) of patients referred for evaluation of IDA from 2008 to 2012. Iron deficiency anemia was diagnosed using clinical laboratory tests. The results of , colonoscopy, and pathology specimens along with demographic data were abstracted and analyzed using Stata.
The mean age was 61.9 years, and 50.5% were women. In total, 189 patients (45%) had gross gastrointestinal (GI) bleeding. The most frequent diagnoses were gastritis (40%), benign colonic lesions (13%), esophagitis (9%), gastric ulcer (6%), and duodenitis (6%). GI bleeding was significantly more frequent in men ( = 0.001). Benign and malignant colonic lesions were significantly more present among older patients: 16% vs 6% ( = .005) and 5% vs 0% ( = .008), respectively. Colitis was more prevalent in younger patients (⩽50): 11% vs 2% ( = .001). In patients with gross lower GI bleeding, the top diagnoses were gastritis (25%), benign colon tumors (10%), and duodenitis (6%). Colon cancer was diagnosed among 15 patients, and all these patients were older than 50 years of age.
Gastritis and colonic lesions are most common associated lesions with IDA among African Americans. So bidirectional endoscopy is required for unrevealing of the cause of IDA in asymptomatic patients.
缺铁性贫血（IDA）是一种常见疾病，与许多严重疾病相关。然而，非裔美国患者中关于IDA相关胃肠道疾病的评估结果尚缺乏。
确定非裔美国IDA患者尤其是年轻男性中最常见的胃肠道病变。
我们回顾了2008年至2012年因IDA评估而转诊患者的病历（n = 422）。通过临床实验室检查诊断缺铁性贫血。提取结肠镜检查、病理标本结果以及人口统计学数据，并使用Stata进行分析。
平均年龄为61.9岁，50.5%为女性。共有189例患者（45%）出现明显的胃肠道（GI）出血。最常见的诊断为胃炎（40%）、良性结肠病变（13%）、食管炎（9%）、胃溃疡（6%）和十二指肠炎（6%）。男性GI出血明显更常见（P = 0.001）。老年患者中良性和恶性结肠病变明显更多见：分别为16%对6%（P = 0.005）和5%对0%（P = 0.008）。结肠炎在年轻患者（≤50岁）中更常见：11%对2%（P = 0.001）。在明显下消化道出血的患者中，最常见的诊断为胃炎（25%）、良性结肠肿瘤（10%）和十二指肠炎（6%）。15例患者被诊断为结肠癌，所有这些患者年龄均超过50岁。
胃炎和结肠病变是非裔美国人中与IDA最常见的相关病变。因此，对于无症状患者，需要进行双向内镜检查以揭示IDA的病因。
