Department of Family Medicine and Primary Care, The University of Hong Kong, Rm 1-01, 1/F, Jockey Club Building for Interdisciplinary Research, 5 Sassoon Road, Pokfulam, Hong Kong SAR, China.
Centre for Health Economics Research and Evaluation, University of Technology Sydney, Ultimo, Australia.
Qual Life Res. 2018 Sep;27(9):2349-2359. doi: 10.1007/s11136-018-1887-3. Epub 2018 May 24.
To estimate population norms for the SF-6D health preference (utility) scores derived from the MOS SF-36 version 1 (SF-36v1), SF-36 version 2 (SF-36v2), and (SF-12v2) health surveys collected from a representative adult sample in Hong Kong, and to assess differences in SF-6D scores across sociodemographic subgroups.
A random telephone survey of 2410 Chinese adults was conducted. All respondents completed questionnaires on sociodemographics and presence of chronic diseases (hypertension, diabetes, chronic rheumatism, chronic lung diseases, stroke, and mental illness), and the short-form 36-item health survey (SF-36) version 1, and selected items of the SF-36v2 that were different from those of SF-36v1. Responses of short-form 12-item health survey (SF-12) were extracted from responses of the SF-36 items. SF-6D health utility scores were derived from SF-36 version 1 (SF-6D), SF-36 version 2 (SF-6D), and SF-12 version 2 (SF-6D) using Hong Kong SF-6D value set.
Population norms of SF-6D, SF-6D, and SF-6D for the Hong Kong Chinese were 0.7947 (± 0.0048), 0.7862 (± 0.0049), and 0.8147 (± 0.0050), respectively. Three SF-6D scores were highly correlated (0.861-0.954), and had a high degree of reliability and absolute agreement. Males had higher health utility scores (SF-6D: 0.0025; SF-6D: 0.025; SF-6D: 0.018) but reported less problems in all the dimensions than women. Respondents with a higher number of chronic diseases had lower SF-6D scores. Among all respondents with one or more chronic diseases, those with hypertension scored the highest whereby those with mental illness scored the least.
The SF-6D utility scores derived from different SF-36 or SF-12 health surveys were different. The population norms based on these three health surveys enable the normative comparisons of health utility scores from specific population or patient groups, and provide estimates of age-gender adjusted health utility scores for health economic evaluations.
从香港代表性成年样本中收集的 MOS SF-36 版本 1（SF-36v1）、SF-36 版本 2（SF-36v2）和（SF-12v2）健康调查中，估算 SF-6D 健康偏好（效用）评分的人群正常值，并评估不同社会人口统计学亚组之间的 SF-6D 评分差异。
对 2410 名中国成年人进行了随机电话调查。所有受访者均完成了关于社会人口统计学和慢性病（高血压、糖尿病、慢性风湿性疾病、慢性肺部疾病、中风和精神疾病）存在情况的问卷，以及简短的 36 项健康调查（SF-36）版本 1，以及 SF-36v1 不同的 SF-36v2 选定项目。简短的 12 项健康调查（SF-12）的回答从 SF-36 项目的回答中提取出来。SF-6D 健康效用评分是从 SF-36 版本 1（SF-6D）、SF-36 版本 2（SF-6D）和 SF-12 版本 2（SF-6D）使用香港 SF-6D 值集得出的。
香港中国人的 SF-6D、SF-6D 和 SF-6D 的人群正常值分别为 0.7947（±0.0048）、0.7862（±0.0049）和 0.8147（±0.0050）。三个 SF-6D 评分高度相关（0.861-0.954），具有高度可靠性和绝对一致性。男性的健康效用评分更高（SF-6D：0.0025；SF-6D：0.025；SF-6D：0.018），但报告的所有维度的问题都比女性少。患有较多慢性病的受访者的 SF-6D 评分较低。在所有患有一种或多种慢性病的受访者中，患有高血压的受访者得分最高，而患有精神疾病的受访者得分最低。
从不同的 SF-36 或 SF-12 健康调查得出的 SF-6D 效用评分不同。基于这三种健康调查的人群正常值可以对特定人群或患者群体的健康效用评分进行规范比较，并为健康经济评估提供年龄性别调整后的健康效用评分估计。
