Entomology and Nematology Department, University of Florida, Gainesville, FL, USA.
Anastasia Mosquito Control District, St Augustine, FL, USA.
Pest Manag Sci. 2018 Dec;74(12):2699-2706. doi: 10.1002/ps.5088. Epub 2018 Jul 20.
Mosquito mortality has been documented in numerous studies of spatial repellents but the concentration-dependent toxicity of spatial repellent vapors has not been documented. To address this issue, prallethrin, flumethrin, metofluthrin, transfluthrin, and meperfluthrin were selected for comparative study against Aedes albopictus (Skuse), Ae. aegypti (L.), Culex quinquefasciatus Say, and Anopheles quadrimaculatus Say. Mosquito were exposed to vapors of each chemical for 2, 4, and 24 h with mortality recorded at each time point. A second experiment involved exposing mosquitoes to vapors for 2 h, then transferring them to untreated holding containers and held for 24 h. For these mosquitoes, readings were only taken after 24 h to allow for metabolic detoxification and recovery.
LC and LC data indicated that transfluthrin and meperfluthrin had the greatest toxicity across all species, followed by metofluthrin, prallethrin, and flumethrin.
Our findings, through the direct comparison of these compounds, suggest that transfluthrin, meperfluthrin, and metofluthrin be considered for further development. The vapor toxicity for the aforementioned compounds significantly exceeds prallethrin, which is currently market available as an adulticidal active ingredient in public health pest control. © 2018 Society of Chemical Industry.
在许多空间驱避剂的研究中都记录了蚊虫的死亡率，但空间驱避剂蒸气的浓度依赖性毒性尚未记录。为了解决这个问题，选择了炔丙菊酯、氯菊酯、氯氟醚菊酯、四氟甲醚菊酯和氯菊酯进行比较研究，以对抗白纹伊蚊（Skuse）、埃及伊蚊（L.）、致倦库蚊和三带喙库蚊。将蚊子暴露在每种化学物质的蒸气中 2、4 和 24 小时，并在每个时间点记录死亡率。第二个实验涉及将蚊子暴露在蒸气中 2 小时，然后将它们转移到未处理的保持容器中并保持 24 小时。对于这些蚊子，仅在 24 小时后进行读数，以允许代谢解毒和恢复。
LC 和 LC 数据表明，四氟甲醚菊酯和氯菊酯在所有物种中的毒性最大，其次是氯氟醚菊酯、炔丙菊酯和氯菊酯。
通过对这些化合物的直接比较，我们的发现表明，四氟甲醚菊酯、氯菊酯和氯氟醚菊酯可考虑进一步开发。上述化合物的蒸气毒性明显超过了炔丙菊酯，炔丙菊酯目前作为公共卫生害虫控制的一种杀成虫活性成分在市场上有售。 © 2018 化学工业协会。
