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[变应性鼻炎的患病率及危险因素:一项Meta分析]

[Prevalence and risk factors of allergic rhinitis: a Meta-analysis].

作者信息

Hu S J, Wei P, Kou W, Wu X F, Liu M Y, Chen C, Yao H B

机构信息

Department of Otorhinolaryngology Head and Neck Surgery,Children's Hospital of Chongqing Medical University,Chongqing,400014,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Oct 5;31(19):1485-1491. doi: 10.13201/j.issn.1001-1781.2017.19.006.

DOI:10.13201/j.issn.1001-1781.2017.19.006
PMID:29798100
Abstract

To clarify the morbidity and risk factors of allergic rhinitis (AR) in China so as to provide scientific basis for prevention of AR in the relevant populations.Pubmed,Embase,Web of science,Cochrane Library,CNKI,VIP,Wanfang Data,CBM databases were searched for associated studies. The prevalence and risk factors of AR in China were retrieved from individual studies and the pooled estimates generated by R3.2.3 software.Thirty-one cross-sectional studies were included in the Meta-analysis. The results indicated that the incidences of AR in Chinese children were 15.79%(95% 15.13-16.45).The highest prevalence is 17.20% in central China,the lowest is 13.94% in eastern China. The incidences of AR in Chinese adult were 13.26% (95% 12.05-14.47).The highest prevalence is 15.45% in southern China,the lowest is 10.93% in southwestern China. The pooled odds ratio (OR) values of family history (5.40),dust exposure history (2.04),drug allergy history (2.83),history of asthma(4.45),environmental tobacco smoking(ETS)(2.00),water damage (1.50),upholstering(1.41),pollen allergy(17.18),molds(1.31),keeping pets (1.29),cockroach (1.69).A study on the epidemic tendency of AR in China showed the morbidity of AR in Chinese children is higher than adult. Moreover,prevalence vary from region to region. Eleven kinds of risk factors mentioned above play imperative roles in the pathogenesis of AR. The early interventions which are associated with risk factors should be implemented in AR.

摘要

为明确中国变应性鼻炎(AR)的发病率及危险因素,为相关人群AR的预防提供科学依据。检索了PubMed、Embase、Web of science、Cochrane图书馆、中国知网、维普、万方数据、中国生物医学文献数据库等相关研究。从个体研究及R3.2.3软件生成的合并估计值中获取中国AR的患病率及危险因素。Meta分析纳入了31项横断面研究。结果表明,中国儿童AR的发病率为15.79%(95% 15.13 - 16.45)。中部地区患病率最高,为17.20%,东部地区最低,为13.94%。中国成人AR的发病率为13.26%(95% 12.05 - 14.47)。南部地区患病率最高,为15.45%,西南部地区最低,为10.93%。家族史(5.40)、接触粉尘史(2.04)、药物过敏史(2.83)、哮喘史(4.45)、环境烟草烟雾(ETS)(2.00)、水患(1.50)、室内装饰(1.41)、花粉过敏(17.18)、霉菌(1.31)、养宠物(1.29)、蟑螂(1.69)的合并比值比(OR)值。一项关于中国AR流行趋势的研究表明,中国儿童AR的发病率高于成人。此外,患病率因地区而异。上述11种危险因素在AR发病机制中起重要作用。应针对AR实施与危险因素相关的早期干预措施。

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