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阻塞性睡眠呼吸暂停低通气综合征与慢性耳鸣相关性的初步研究

[A preliminary study on the correlation between obstructive sleep apnea hypopnea syndrome and chronic tinnitus].

作者信息

Liu X L, Wang J, Hong Z J, Zhongshan M F

机构信息

Department of Otolaryngology, Vertigo Clinic Treatment Center,the First Affiliated Hospital of Dalian Medical University, Dalian, 116011,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Apr;32(8):575-578. doi: 10.13201/j.issn.1001-1781.2018.08.004.

DOI:10.13201/j.issn.1001-1781.2018.08.004
PMID:29798138
Abstract

To investigate and analyze the chronic tinnitus prevalence and its related factors in OSAHS patients.We studied 115 patients who were diagnosed with OSAHS by polysomnography.All patients BMI were calculated. The amount of patients accompanying tinnitus was calculated by investigating the history of tinnitus. Univariate and multivariate logistic analyzes were used to calculate the association between gender, age, hearing loss, BMI, and the lowest SPO₂ with tinnitus. The differences in tinnitus prevalence among different age groups and gender were compared using chi-square test.①The prevalence of tinnitus in 115 OSAHS patients was 38.26% (44/115). ②Between the ages of 31-80 years, the prevalence of tinnitus in every 10-year-old group was 9.09%,6.82%,11.36%,38.64%,and 29.55%,respectively.There was a significant difference between the age groups (χ²=14.55,<0.01). The prevalence of female was 44.12%(15/34) which was higher than the male 35.80%(29/81), there was no significant difference (χ²=0.70,>0.05). ③The results of univariate and multivariate logistic regression analysis showed that sex, BMI and lowest SPO₂ had no correlation with tinnitus in patients with OSAHS, while age and hearing loss were independent correlates of tinnitus(<0.05).More than 1/3 of patients with OSAHS had chronic tinnitus, both age and hearing loss maybe the risk factors of tinnitus in patients with OSAHS, but neither BMI nor the lowest SPO₂ was clearly related to chronic tinnitus.

摘要

调查分析阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者慢性耳鸣的患病率及其相关因素。我们研究了115例经多导睡眠图诊断为OSAHS的患者。计算所有患者的体重指数(BMI)。通过询问耳鸣病史计算伴有耳鸣的患者数量。采用单因素和多因素逻辑回归分析计算性别、年龄、听力损失、BMI以及最低血氧饱和度(SPO₂)与耳鸣之间的关联。使用卡方检验比较不同年龄组和性别的耳鸣患病率差异。①115例OSAHS患者中耳鸣患病率为38.26%(44/115)。②在31 - 80岁之间,每10岁年龄组的耳鸣患病率分别为9.09%、6.82%、11.36%、38.64%和29.55%。年龄组之间存在显著差异(χ² = 14.55,P < 0.01)。女性患病率为44.12%(15/34),高于男性的35.80%(29/81),但差异无统计学意义(χ² = 0.70,P > 0.05)。③单因素和多因素逻辑回归分析结果显示,OSAHS患者的性别、BMI和最低SPO₂与耳鸣无相关性,而年龄和听力损失是耳鸣的独立相关因素(P < 0.05)。超过1/3的OSAHS患者患有慢性耳鸣,年龄和听力损失可能是OSAHS患者耳鸣的危险因素,但BMI和最低SPO₂均与慢性耳鸣无明显关联。

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