Siddiqui Ali Nasir, Hussain Salman, Siddiqui Nahida, Khayyam Khalid Umer, Tabrez Shams, Sharma Manju
Department of Pharmaceutical Medicine, School of Pharmaceutical Education and Research, Hamdard University, New Delhi, 110062, India.
Department of Pharmacognosy & Phytochemistry, School of Pharmaceutical Education and Research, Hamdard University, New Delhi, 110062, India.
Diabetes Metab Syndr. 2018 Nov;12(6):1101-1107. doi: 10.1016/j.dsx.2018.05.009. Epub 2018 May 23.
Despite significant efforts made to control tuberculosis (TB) through DOTS program, the increasing burden of diabetes mellitus (DM) threatens the progress in reducing TB-related mortality, particularly in developing countries. In recent years, TB-DM comorbidity continues to remain high in countries where DM is on rampant. DM increases the risk of TB, reactivates the dormant TB and worsens the TB treatment outcome. The present review highlights the current findings regarding the prevalence and association of TB-DM comorbidity along with their public health implications. This review will increase the awareness among researchers, policymakers and clinicians, regarding the current scenario of TB-DM association.
尽管通过直接观察短程治疗（DOTS）计划在控制结核病（TB）方面做出了巨大努力，但糖尿病（DM）负担的不断增加威胁着降低结核病相关死亡率方面取得的进展，尤其是在发展中国家。近年来，在糖尿病肆虐的国家，结核病-糖尿病合并症的比例持续居高不下。糖尿病会增加患结核病的风险，使潜伏性结核病复发，并恶化结核病的治疗效果。本综述重点介绍了关于结核病-糖尿病合并症的患病率、关联及其对公共卫生影响的当前研究结果。这篇综述将提高研究人员、政策制定者和临床医生对结核病-糖尿病关联现状的认识。
