结核病相关糖尿病：完全治愈后是否可逆？
Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?
作者信息
Aftab Huma, Christensen Dirk L, Ambreen Atiqa, Jamil Mohammad, Garred Peter, Petersen Jørgen H, Nielsen Susanne D, Bygbjerg Ib C
机构信息
Section of Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Gulab Devi Chest Hospital, Lahore, Pakistan.
出版信息
Am J Trop Med Hyg. 2017 Oct;97(4):1099-1102. doi: 10.4269/ajtmh.16-0816. Epub 2017 Aug 18.
Abstract
Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.
摘要
在巴基斯坦，对新诊断出肺结核（TB）的患者进行空腹血糖（FPG）筛查以检测糖尿病（DM）。在治疗肺结核时，观察到空腹血糖显著下降。新诊断出患有糖尿病的患者中，分别有46%和62%在3个月和6个月后不再有高血糖症状。已知患有糖尿病的患者在接受肺结核治疗时，空腹血糖水平也显著下降，但3个月后无人血糖正常，6个月后有9.2%的人血糖正常。因此，与肺结核相关的糖尿病可能在压力终止时减轻，妊娠糖尿病的情况也是如此。然而，由于应激性高血糖可能与后续患糖尿病的风险相关，建议进行随访。
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