Javanmard Ehsan, Niyyati Maryam, Ghasemi Erfan, Mirjalali Hamed, Asadzadeh Aghdaei Hamid, Zali Mohammad Reza
Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Biostatistics, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Acta Trop. 2018 Sep;185:193-203. doi: 10.1016/j.actatropica.2018.05.014. Epub 2018 May 24.
Blastocystis is a prevalent eukaryotic microorganism that has been frequently reported from the stool samples of human and animals, all over the world. The prevalence of this parasite has close correlation with the climate and hygiene situation of studied populations. For the current study, English and Persian databases were searched for the following terms: "Blastocystis hominis", "Blastocystis sp.", "Intestinal Parasites", "Prevalence" and "Iran". In order to data analysis and assess the possibility of publication bias, STATA v11 and Begg's Funnel plot were employed respectively. From 605 searched cases, 86 publications met our criteria for the analysis. The pooled prevalence of Blastocystis was 9.1% (95%CI: 8.2%, 10.1%). The results represented that the prevalence of the parasite using molecular techniques or cultivation followed by molecular techniques (20.89%) was higher than only microscopical examination (8.96%). The prevalence rate of Blastocystis according to human development index was 7.6%, 7.2%, 11.9%, 13.4%, and 3.3% for ranks 1 to 5, respectively. This is the first study signifying the prevalence of Blastocystis regarding the human development index and climate conditions. The findings represented that although human development index, low levels of socioeconomic situations together with appropriate climate such as sufficient humidity and high temperature increase the chance of transmission of Blastocystis in a society.
芽囊原虫是一种常见的真核微生物，在世界各地人类和动物的粪便样本中经常被报道。这种寄生虫的流行率与所研究人群的气候和卫生状况密切相关。在本研究中，我们在英文和波斯文数据库中搜索了以下术语：“人芽囊原虫”、“芽囊原虫属”、“肠道寄生虫”、“流行率”和“伊朗”。为了进行数据分析和评估发表偏倚的可能性，我们分别使用了STATA v11软件和Begg漏斗图。在搜索到的605个案例中，有86篇出版物符合我们的分析标准。芽囊原虫的合并流行率为9.1%（95%置信区间：8.2%，10.1%）。结果表明，使用分子技术或先培养后用分子技术检测到的寄生虫流行率（20.89%）高于仅通过显微镜检查的流行率（8.96%）。根据人类发展指数，芽囊原虫在前五个等级中的流行率分别为7.6%、7.2%、11.9%、13.4%和3.3%。这是第一项表明芽囊原虫流行率与人类发展指数和气候条件之间关系的研究。研究结果表明，尽管人类发展指数较低、社会经济状况较差，但适宜的气候条件，如充足的湿度和高温，会增加社会中芽囊原虫传播的机会。
