Metabolism and excretion of iopentol in the pig.

The metabolism of iopentol was examined in pigs. The search was focused on the urine and bile excreted during the first day after intravenous injection of a high dose. Chromatographic methods (both TLC and HPLC) indicated that the maximum amount of metabolites was less than 1 per cent of the given dose in urine and less than 0.3 per cent in the bile.