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双能X线吸收法与定量超声评估青少年骨骼健康的一致性:PRO-BONE研究

Agreement Between Dual-Energy X-Ray Absorptiometry and Quantitative Ultrasound to Evaluate Bone Health in Adolescents: The PRO-BONE Study.

作者信息

Torres-Costoso Ana, Vlachopoulos Dimitris, Ubago-Guisado Esther, Ferri-Morales Asunción, Cavero-Redondo Iván, Martínez-Vizcaino Vicente, Gracia-Marco Luis

机构信息

1 University of Castilla-La Mancha.

2 University of Exeter.

出版信息

Pediatr Exerc Sci. 2018 Nov 1;30(4):466-473. doi: 10.1123/pes.2017-0217. Epub 2018 May 26.

DOI:10.1123/pes.2017-0217
PMID:29804497
Abstract

PURPOSE

The present study aims to investigate the association between dual-energy X-ray absorptiometry (DXA) and quantitative ultrasound (QUS) parameters and the intermethods agreement in active males.

METHODS

In this cross-sectional study, bone health (by DXA and calcaneal QUS), physical activity (by accelerometers), and anthropometrics measurements were assessed in 117 active adolescents (12-14 y old). Bivariate correlation coefficients were calculated to assess the relationships between DXA standard regions of interest and QUS parameters. Intraclass correlation coefficients and Bland-Altman plots were used to assess the level of agreement between bone mineral content regions derived from DXA and stiffness index. The measurements were z score transformed for comparison.

RESULTS

Most QUS parameters were positive and significantly correlated with DXA outcomes (stiffness index: r = .43-.52; broadband ultrasound attenuation: r = .50-.58; speed of sound: r = .25-.27) with the hip showing the highest correlations. Moreover, the present study found fair to good intraclass correlation coefficients of agreement (.60-.68) between DXA and QUS to assess bone health. The Bland-Altman analysis showed a limited percentage of outliers (3.2%-8.6%).

CONCLUSION

QUS device could represent an acceptable alternative method to assess bone health in active adolescent males.

摘要

目的

本研究旨在调查双能X线吸收法(DXA)和定量超声(QUS)参数之间的关联以及活跃男性中两种方法的一致性。

方法

在这项横断面研究中,对117名活跃青少年(12 - 14岁)进行了骨健康评估(通过DXA和跟骨QUS)、身体活动评估(通过加速度计)以及人体测量。计算双变量相关系数以评估DXA标准感兴趣区域与QUS参数之间的关系。使用组内相关系数和Bland-Altman图来评估DXA得出的骨矿物质含量区域与硬度指数之间的一致性水平。对测量值进行z分数转换以进行比较。

结果

大多数QUS参数为正值,且与DXA结果显著相关(硬度指数:r = 0.43 - 0.52;宽带超声衰减:r = 0.50 - 0.58;声速:r = 0.25 - 0.27),其中髋部的相关性最高。此外,本研究发现DXA和QUS之间评估骨健康的组内相关系数一致性为中等至良好(0.60 - 0.68)。Bland-Altman分析显示异常值的百分比有限(3.2% - 8.6%)。

结论

QUS设备可作为评估活跃青少年男性骨健康的一种可接受的替代方法。

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