Center for Information Technology of Sports and Health, Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences , Hefei 230031, China.
Int J Environ Res Public Health. 2021 Oct 28;18(21):11336. doi: 10.3390/ijerph182111336.
To evaluate the bone response to an 8 month aerobic gymnastics training program in young opioid-addicted women.
Randomized controlled trial (parallel design).
Women's Specific Drug Rehabilitation Center in China.
One hundred and two young women with low bone quality and previous opioid addiction were divided into two groups: (a) the low bone quality intervention experimental group (n = 55; age: 30.3 ± 6.1) and (b) the low bone quality observed control group (observation group; n = 47; age: 29.0 ± 5.3).
The intervention group took aerobic gymnastics regularly for 80 min/d and 5 d/wk for 8 months and completed follow-up testing.
Substance use history and other life habits affecting bone quality were assessed by questionnaire-based interviews. Bone quality (stiffness-index, T-score, Z-score) was examined with quantitative ultrasound. Anthropometric characteristics (body weight, fat-free mass, fat mass) were obtained by bioelectrical impedance analysis.
After the 8 month intervention, the stiffness index of bone quality increased significantly (before: 82 ± 6, after: 108 ± 14, < 0.05) in the experimental group. However, the bone quality did not change significantly in the controls (before: 79 ± 10, after: 77 ± 13, > 0.05). The bone change in the difference group was significant (experimental group: 31.7% vs observation group: -0.03%). Fat mass decreased in the experimental group (experimental group: before: 19.6 ± 3.7 kg, after: 18.8 ± 4.0 kg, < 0.05). Meanwhile, the change in fat-free mass was the determination of the change in bone quality in the experimental group.
Our results suggested that aerobic gymnastics intervention can be an effective strategy for the prevention and treatment of drug-induced osteoporosis in detoxification addicts.
评估 8 个月有氧运动体操训练方案对年轻阿片类药物成瘾女性的骨反应。
随机对照试验（平行设计）。
中国女性特定药物康复中心。
102 名低骨量且有阿片类药物滥用史的年轻女性被分为两组：（a）低骨量干预实验组（n=55；年龄：30.3±6.1）和（b）低骨量观察对照组（观察组；n=47；年龄：29.0±5.3）。
实验组定期进行 80 分钟/天、5 天/周的有氧运动体操，共 8 个月，并完成随访测试。
通过问卷调查访谈评估影响骨质量的药物使用史和其他生活习惯。使用定量超声检查骨质量（刚度指数、T 评分、Z 评分）。通过生物电阻抗分析获得人体测量特征（体重、去脂体重、脂肪量）。
经过 8 个月的干预，实验组的骨质量刚度指数显著增加（干预前：82±6，干预后：108±14， <0.05）。然而，对照组的骨质量没有明显变化（对照组：干预前：79±10，干预后：77±13， >0.05）。实验组与对照组之间的骨变化差异显著（实验组：31.7%比对照组：-0.03%）。实验组的脂肪量减少（实验组：干预前：19.6±3.7kg，干预后：18.8±4.0kg， <0.05）。同时，去脂体重的变化是实验组骨质量变化的决定因素。
我们的研究结果表明，有氧运动体操干预可能是戒毒成瘾者预防和治疗药物性骨质疏松的有效策略。
Zotero 插件