Niendorf H P, Felix R, Laniado M, Schörner W, Kornmesser W, Claussen C
Department of Radiology, FB Medizin, Schering AG, Berlin, West Germany.
Acta Radiol Suppl. 1986;369:561-3.
One hundred and fifty gadolinium(Gd)-DTPA studies in patients with intracranial tumors were performed. In meningiomas (n = 37) Gd-DTPA is useful to delineate isointense tumors. In acoustic neuromas (n = 16) Gd-DTPA helps to identify intracanalicular tumor tissue. In pituitary adenomas (n = 16) para- or suprasellar tumor extension can be better appreciated after Gd-DTPA injection. In glioblastomas (n = 23) Gd-DTPA provides data on differential diagnosis through the characteristic shape of enhancement. In a variety of tumor types the high contrast between enhancing tumor tissue and adjacent structures facilitates therapy planning. Fast imaging sequences now allow for dynamic Gd-DTPA studies. The time-course of enhancement may increase specificity of magnetic resonance imaging.
对150例颅内肿瘤患者进行了钆(Gd)-二乙三胺五乙酸(DTPA)研究。在脑膜瘤(n = 37)中,Gd-DTPA有助于勾勒等密度肿瘤。在听神经瘤(n = 16)中,Gd-DTPA有助于识别管内肿瘤组织。在垂体腺瘤(n = 16)中,注射Gd-DTPA后可更好地观察鞍旁或鞍上肿瘤扩展情况。在胶质母细胞瘤(n = 23)中,Gd-DTPA通过特征性强化形态提供鉴别诊断数据。在多种肿瘤类型中,强化肿瘤组织与相邻结构之间的高对比度有助于治疗规划。快速成像序列现在允许进行动态Gd-DTPA研究。强化的时间过程可能会提高磁共振成像的特异性。