Zhang L, Long Y, Xiao H, Yang J, Toulon P, Zhang Z
Department of Clinical Laboratory and Pathology, Wuhan Asia Heart Hospital, Wuhan, China.
Heart Center, Wuhan Asia Heart Hospital, Wuhan, China.
Int J Lab Hematol. 2018 Oct;40(5):503-507. doi: 10.1111/ijlh.12864. Epub 2018 May 27.
Individualized anticoagulation management and improvement of the safety and effectiveness of oral anticoagulant have always been the focus of clinicians' attention. D-dimer, a sensitive marker of thrombosis and coagulation activation, is not only traditionally used in the diagnosis of venous thromboembolism, acute aortic dissection, and disseminated intravascular coagulation but can also be used as a helpful marker in the management of oral anticoagulant, including evaluating the anticoagulation quality, predicting clinical outcomes, and determining the optimal duration and intensity of anticoagulation.
个体化抗凝管理以及提高口服抗凝剂的安全性和有效性一直是临床医生关注的焦点。D - 二聚体是血栓形成和凝血激活的敏感标志物，不仅传统上用于静脉血栓栓塞、急性主动脉夹层和弥散性血管内凝血的诊断，还可作为口服抗凝剂管理中的有用标志物，包括评估抗凝质量、预测临床结局以及确定抗凝的最佳持续时间和强度。
