asperfurandiones A 和 B，两种来自海洋来源真菌的抗真菌 furandione 类似物。
Asperfurandiones A and B, two antifungal furandione analogs from a marine-derived fungus .
机构信息
Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center, Ningbo University , Ningbo , China.
Key Laboratory of Marine Biotechnology of Zhejiang Province, Ningbo University , Ningbo , China.
出版信息
Nat Prod Res. 2019 Dec;33(23):3404-3408. doi: 10.1080/14786419.2018.1480622. Epub 2018 May 28.
Two new furandione derivatives, designated as asperfurandiones A () and B (), were isolated from the solid culture of the marine-derived fungus . Their structures were elucidated using a combination of mass spectrometry and NMR spectroscopy. Additionally, asperfurandiones A and B both showed moderate antifungal activity against , , and with MIC values of 64 μg/mL.
从海洋来源的真菌 Aspergillus sp. 的固体培养物中分离得到了两种新的呋喃二酮衍生物，分别命名为asperfurandiones A () 和 B ()。它们的结构通过质谱和 NMR 光谱的组合来阐明。此外，asperfurandiones A 和 B 均显示出对 的中等抗真菌活性，MIC 值为 64 μg/mL。
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