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Impella在高危经皮冠状动脉介入治疗中的作用。

The role of Impella in high-risk percutaneous coronary intervention.

作者信息

Moura-Ferreira Sara, Ladeiras-Lopes Ricardo, MBala Domingas, Rodrigues Alberto, Braga Pedro, Gama Vasco

机构信息

Cardiology Department, Hospital do Divino Espírito Santo, Ponta Delgada, Portugal.

Cardiology Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.

出版信息

Rev Port Cardiol (Engl Ed). 2018 Jul;37(7):623.e1-623.e4. doi: 10.1016/j.repc.2017.05.013. Epub 2018 May 26.

DOI:10.1016/j.repc.2017.05.013
PMID:29807675
Abstract

Percutaneous coronary intervention (PCI) has been increasingly performed in patients with severely depressed left ventricular function and complex coronary lesions, including multivessel disease. Mechanical ventricular assist devices play an increasingly important role in high-risk PCI. Impella CP (Abiomed, Inc.) is a new percutaneous left ventricular assist device, designed for short-term circulatory support. It is a promising option for hemodynamic support in high-risk procedures and can potentially reduce PCI-related complications. The authors present two case reports of high-risk PCI using the Impella CP device. In the setting of low coronary flow reserve, severely depressed left ventricular function and potential hemodynamic instability, the Impella CP device has made it possible to maintain hemodynamic stability during procedures, without being associated with vascular complications.

摘要

经皮冠状动脉介入治疗(PCI)越来越多地应用于左心室功能严重受损且伴有复杂冠状动脉病变(包括多支血管病变)的患者。机械心室辅助装置在高危PCI中发挥着越来越重要的作用。Impella CP(Abiomed公司)是一种新型经皮左心室辅助装置,设计用于短期循环支持。它是高危手术中血流动力学支持的一个有前景的选择,并有可能减少与PCI相关的并发症。作者介绍了两例使用Impella CP装置进行高危PCI的病例报告。在冠状动脉血流储备低、左心室功能严重受损和潜在血流动力学不稳定的情况下,Impella CP装置使得在手术过程中维持血流动力学稳定成为可能,且未出现血管并发症。

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The role of Impella in high-risk percutaneous coronary intervention.Impella在高危经皮冠状动脉介入治疗中的作用。
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引用本文的文献

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DCM Support: cell therapy and circulatory support for dilated cardiomyopathy patients with severe ventricular impairment.DCM 支持:用于严重心室功能障碍的扩张型心肌病患者的细胞治疗和循环支持。
ESC Heart Fail. 2023 Aug;10(4):2664-2671. doi: 10.1002/ehf2.14393. Epub 2023 May 15.
2
Case report: Cytokine therapy and an intracoronary autologous bone marrow-derived cell infusion with Impella support in a patient with dilated cardiomyopathy and a severely reduced ejection fraction.病例报告:一名扩张型心肌病且射血分数严重降低的患者,在Impella支持下接受细胞因子治疗及冠状动脉内自体骨髓源性细胞输注。
Front Cardiovasc Med. 2022 Sep 12;9:1002508. doi: 10.3389/fcvm.2022.1002508. eCollection 2022.