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甲状旁腺功能减退引发癫痫发作:当癫痫诊断不成立时。

Hypoparathyroidism Causing Seizures: When Epilepsy Does Not Fit.

作者信息

Seedat Faheem, Daya Reyna, Bhana Sindeep A

机构信息

Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

出版信息

Case Rep Med. 2018 Apr 1;2018:5948254. doi: 10.1155/2018/5948254. eCollection 2018.

DOI:10.1155/2018/5948254
PMID:29808096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5902126/
Abstract

A 24-year-old man presented to the Chris Hani Baragwanath Academic Hospital emergency department with recurrent seizures having previously been diagnosed with epilepsy from age 14. The biochemical investigations and brain imaging were suggestive of seizures secondary to hypocalcemia, and a diagnosis of idiopathic hypoparathyroidism was confirmed. After calcium and vitamin D replacement, the patient recovered well and is seizure free, and off antiepileptic therapy. This case highlights the occurrence of brain calcinosis in idiopathic hypoparathyroidism; the occurrence of acute symptomatic seizures due to provoking factors other than epilepsy; and the importance, in the correct clinical setting, of considering alternative, and sometimes treatable, causes of seizures other than epilepsy.

摘要

一名24岁男性因反复癫痫发作就诊于克里斯·哈尼·巴拉格瓦纳特学术医院急诊科,他自14岁起就被诊断为癫痫。生化检查和脑部影像学检查提示癫痫发作继发于低钙血症,特发性甲状旁腺功能减退症的诊断得到证实。经过钙和维生素D替代治疗后,患者恢复良好,不再发作癫痫,且停用了抗癫痫治疗。该病例突出了特发性甲状旁腺功能减退症中脑钙化的发生;由癫痫以外的诱发因素导致急性症状性癫痫发作的情况;以及在正确的临床背景下,考虑癫痫以外其他可替代的、有时可治疗的癫痫病因的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8024/5902126/4423a7df8302/CRIM2018-5948254.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8024/5902126/8bd70655f1c0/CRIM2018-5948254.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8024/5902126/e2671ef72dae/CRIM2018-5948254.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8024/5902126/4423a7df8302/CRIM2018-5948254.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8024/5902126/8bd70655f1c0/CRIM2018-5948254.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8024/5902126/e2671ef72dae/CRIM2018-5948254.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8024/5902126/4423a7df8302/CRIM2018-5948254.003.jpg

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