Shannon K M, Ammann A J
J Pediatr. 1985 Feb;106(2):332-42. doi: 10.1016/s0022-3476(85)80320-6.
The acquired immunodeficiency syndrome has been observed with increasing frequency in children with associated hemophilia, high-risk environmental backgrounds, and blood transfusions. AIDS should be considered in the differential diagnosis of childhood immunodeficiency, and it must be distinguished from congenital disorders. We emphasize the importance of epidemiologic, clinical, and laboratory data in diagnosis and aggressive management of infectious complications. The relationship between human retrovirus infection and AIDS remains to be precisely defined, especially with regard to cofactors that may play a role in the development of severe immunodeficiency following exposure to the agent.
在患有血友病、处于高危环境背景以及接受输血的儿童中，获得性免疫缺陷综合征的发病率日益增高。在儿童免疫缺陷的鉴别诊断中应考虑艾滋病，且必须将其与先天性疾病区分开来。我们强调流行病学、临床及实验室数据在诊断和积极处理感染性并发症方面的重要性。人类逆转录病毒感染与艾滋病之间的关系仍有待精确界定，尤其是关于在接触该病原体后可能在严重免疫缺陷发展过程中起作用的辅助因素。
