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艾滋病中的低丙种球蛋白血症及抗HIV抗体阴性

Hypogammaglobulinaemia and negative anti-HIV antibodies in AIDS.

作者信息

Español T, Garcia-Armuí R, Bofill A, Suñé J, Bertran J M

机构信息

Deparment of Immunology, Pediatric Hospital, R S Valle Hebrón, Barcelona, Spain.

出版信息

Arch Dis Child. 1987 Aug;62(8):853-4. doi: 10.1136/adc.62.8.853.

DOI:10.1136/adc.62.8.853
PMID:3662596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1778503/
Abstract

Repeated bacterial infections are frequent in children with AIDS owing to the B cell abnormalities produced by HIV infection. We report on two infants who presented with hypogammaglobulinaemia and with no HIV antibodies, but with epidemiological, immunological, and clinical features of AIDS.

摘要

由于HIV感染导致的B细胞异常,艾滋病患儿经常反复发生细菌感染。我们报告了两名婴儿,他们表现为低丙种球蛋白血症,且无HIV抗体,但具有艾滋病的流行病学、免疫学和临床特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9a5/1778503/0c40e093fb54/archdisch00695-0096-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9a5/1778503/0c40e093fb54/archdisch00695-0096-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9a5/1778503/0c40e093fb54/archdisch00695-0096-a.jpg

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本文引用的文献

1
Transfusion-associated acquired immune deficiency syndrome in infants.婴儿输血相关获得性免疫缺陷综合征
J Pediatr. 1984 Nov;105(5):731-7. doi: 10.1016/s0022-3476(84)80292-9.
2
Acquired immunodeficiency with reversed T4/T8 ratios in infants born to promiscuous and drug-addicted mothers.滥交且吸毒的母亲所生婴儿出现获得性免疫缺陷伴T4/T8比例倒置。
JAMA. 1983 May 6;249(17):2350-6.
3
Acquired immune deficiency syndrome in childhood.儿童获得性免疫缺陷综合征
Arch Dis Child. 1989 Jan;64(1):135-7. doi: 10.1136/adc.64.1.135.
J Pediatr. 1985 Feb;106(2):332-42. doi: 10.1016/s0022-3476(85)80320-6.