A fragment of the simian virus 40 early genome can induce tumors in nude mice.
作者信息
Pan S, Sompayrac L M, Knowles B B, Danna K J
出版信息
J Virol. 1985 Mar;53(3):988-9. doi: 10.1128/JVI.53.3.988-989.1985.
Abstract
Cell lines transformed by simian virus 40 mutant F8dl (deleted from 0.168 to 0.424 map units, corresponding to the carboxy-terminal 62% of the wild-type simian virus 40 large tumor antigen) are tumorigenic in nude mice. Four of five C3H10T1/2 cell lines transformed by F8dl were tumorigenic in nude mice, whereas two of two wild-type transformants were tumorigenic.
摘要
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本文引用的文献
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Simian virus 40 sequences between 0.168 and 0.424 map units are not required for abortive transformation.
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