Johansson F, Almay B G, von Knorring L, Terenius L, Aström M
Psychiatry Res. 1979 Dec;1(3):231-9. doi: 10.1016/0165-1781(79)90004-0.
Interindividual differences in endorphin levels may relate to widespread changes in adaptive processes, and endorphin levels may thus be related to personality traits. In 40 patients with chronic pain syndromes of both psychogenic and organic origin, endorphin levels in cerebrospinal fluid (CSF) were determined, and the patients completed Eysenck's Personality Inventory (EPI) and the Cesarek Marke Personality Scheme. Twenty-seven of the patients also completed the Zuckerman Sensation Seeking Scale (SSS). As a comparison group 30 healthy volunteers completed the personality inventories. The chronic pain patients were characterized by guilt feelings, need for order, low need for autonomy, and low tendency toward sensation seeking. Low levels of endorphins in CSF were found in patients with high scores on all the subscales in the SSS and low scores on the neuroticism subscale in the EPI.
内啡肽水平的个体差异可能与适应性过程的广泛变化有关，因此内啡肽水平可能与人格特质相关。对40名患有心因性和器质性慢性疼痛综合征的患者，测定其脑脊液（CSF）中的内啡肽水平，患者完成艾森克人格问卷（EPI）和切萨雷克·马克人格量表。其中27名患者还完成了祖克曼感觉寻求量表（SSS）。作为对照组，30名健康志愿者完成了人格量表测试。慢性疼痛患者的特点是有内疚感、需要秩序、自主需求低以及感觉寻求倾向低。在SSS所有分量表得分高且EPI神经质分量表得分低的患者中，发现脑脊液内啡肽水平较低。
