Anaesthesia and Intensive Care Medicine, Royal United Hospital, Bath, BA1 3NG, UK.
Resuscitation Medicine, Bristol Medical School, University of Bristol, Bristol, UK.
Crit Care. 2018 May 29;22(1):139. doi: 10.1186/s13054-018-2058-1.
Adrenaline has been used in the treatment of cardiac arrest for many years. It increases the likelihood of return of spontaneous circulation (ROSC), but some studies have shown that it impairs cerebral microcirculatory flow. It is possible that better short-term survival comes at the cost of worse long-term outcomes. This narrative review summarises the rationale for using adrenaline, significant studies to date, and ongoing research.
肾上腺素在心脏骤停的治疗中已经使用了多年。它增加了自主循环恢复(ROSC)的可能性,但一些研究表明它会损害脑微循环血流。更好的短期存活率可能是以更差的长期预后为代价的。本文综述总结了使用肾上腺素的基本原理、迄今为止的重要研究以及正在进行的研究。