Shetty Preethesh, Hegde Mithra N, Eraly Sunil M
MDS [Conservative Dentistry & Endodontics], A.B.Shetty Memorial Institute Of Dental Sciences, Nitte University, Deralakatte, Mangalore-575018.
MDS [Conservative Dentistry & Endodontics], Ph.D, MAMS, A.B.Shetty Memorial Institute Of Dental Sciences, Nitte University, Deralakatte, Mangalore-575018.
J Clin Exp Dent. 2018 May 1;10(5):e419-e424. doi: 10.4317/jced.54633. eCollection 2018 May.
Renal failure is a process that expresses a loss of functional capacity of the nephrons, independently of its etiology. The most widely used technique to combat renal failure is hemodialysis. Renal failure causes various systemic alterations including oral complications such as variations in the flow and composition of the saliva. Caries is a multifactorial disease and impaired stimulated salivary flow rate and buffering capacity are the best-known risk factors. The present study aims to evaluate the salivary pH, buffering capacity and the flow rate of saliva to the DMFT status in adult hemodialysis patients among the Indian population.
Twenty healthy individuals and sixty patients undergoing hemodialysis were divided into four groups based on the following criteria: Group 1: Control group; healthy individuals,Group 2: Patients before undergoing dialysis or undergoing dialysis<3 months, Group 3: Patients undergoing dialysis since 6 months-2 years, Group 4: Patients undergoing dialysis>2 years. Dental examinations were performed according to the modified WHO oral health survey 2013 criteria and DMFT index. Saliva was collected after pre-stimulation to measuring the flow rate, buffering capacity and pH.
The results exhibited a decrease in the salivary flow rate and buffering capacity with the increase in the time interval of hemodialysis, but salivary pH was found to be increasing with time. A direct relationship was seen between the DMFT scores with the increasing time interval. There was a significant correlation between DMFT index, stimulated salivary flow rate, and buffering capacity in the patients.
Oral health impairment can beacon to grave problems in infection-prone hemodialysis patients. Hence, the patients on hemodialysis should have regular dental examinations and treatment. Regular dental examination and instruction in patients awaiting a renal transplantation is of vital importance to ensure optimal oral health. Saliva, pH, Buffering Capacity, Flow Rate, Hemodialysis, DMFT.
肾衰竭是一个与病因无关的、表示肾单位功能丧失的过程。治疗肾衰竭最广泛使用的技术是血液透析。肾衰竭会引起各种全身改变，包括口腔并发症，如唾液流量和成分的变化。龋齿是一种多因素疾病，刺激唾液流速受损和缓冲能力是最著名的危险因素。本研究旨在评估印度人群中成年血液透析患者的唾液pH值、缓冲能力和唾液流速与龋失补指数（DMFT）状态的关系。
20名健康个体和60名接受血液透析的患者根据以下标准分为四组：第1组：对照组；健康个体；第2组：透析前或透析时间<3个月的患者；第3组：透析6个月至2年的患者；第4组：透析>2年的患者。根据2013年修改后的世界卫生组织口腔健康调查标准和DMFT指数进行口腔检查。在预刺激后收集唾液以测量流速、缓冲能力和pH值。
结果显示，随着血液透析时间间隔的增加，唾液流速和缓冲能力下降，但唾液pH值随时间增加。DMFT评分与时间间隔增加呈直接关系。患者的DMFT指数、刺激唾液流速和缓冲能力之间存在显著相关性。
口腔健康受损可能给易感染的血液透析患者带来严重问题。因此，接受血液透析的患者应定期进行口腔检查和治疗。对等待肾移植的患者进行定期口腔检查和指导对于确保最佳口腔健康至关重要。唾液、pH值、缓冲能力、流速、血液透析、DMFT
