利用19个X染色体短串联重复序列对贵州苗族进行的遗传多样性和单倍型分析。
Genetic diversity and haplotype analysis of Guizhou Miao identified with 19 X-chromosomal short tandem repeats.
作者信息
Han Yanyan, He Guanglin, Gong Sheng, Chen Junying, Jiang Zhigang, Chen Pengyu
机构信息
School of Public Health, Zunyi Medical University, Zunyi, 563099, Guizhou, China.
Institute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, 610041, Sichuan, China.
出版信息
Int J Legal Med. 2019 Jan;133(1):99-101. doi: 10.1007/s00414-018-1871-z. Epub 2018 May 30.
We analyzed Chinese Miao population samples (n = 268) from Guizhou province, Southwest China, with 19 X-chromosomal short tandem repeats (STRs) included in the AGCU X19 amplification kit. The combined PE is 0.999999922 and the combined PDs in males and females are 0.9999999999999999999994 and 0.9999999999998, respectively. The mean paternity exclusion change values are larger than 0.99999996. The HDs in seven linkage groups vary from 0.9324 to 0.9968. Subsequently, comparison among different Chinese populations shows that the substructures of Chinese were significantly influenced by ethno-linguistic rather than geographical boundaries, including most prominently Turkic-speaking and Tibeto-Burman-speaking populations.
我们分析了来自中国西南部贵州省的268份中国苗族人群样本，采用AGCU X19扩增试剂盒中的19个X染色体短串联重复序列（STR）。累积个体识别率为0.999999922，男性和女性的累积父权排除率分别为0.9999999999999999999994和0.9999999999998。平均父权排除变化值大于0.99999996。七个连锁群中的单倍型多样性从0.9324到0.9968不等。随后，不同中国人群之间的比较表明，中国人的亚结构受民族语言而非地理边界的显著影响，其中最突出的包括说突厥语和藏缅语的人群。
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