哪种类型的乳腺癌在环形专用乳腺PET上无法检测到？
Which type of breast cancers is undetectable on ring-type dedicated breast PET?
作者信息
Sasada Shinsuke, Masumoto Norio, Goda Noriko, Kajitani Keiko, Emi Akiko, Kadoya Takayuki, Okada Morihito
机构信息
Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
出版信息
Clin Imaging. 2018 Sep-Oct;51:186-191. doi: 10.1016/j.clinimag.2018.05.010. Epub 2018 May 22.
OBJECTIVES
To assess the factors causing tumor undetectability on ring-type dedicated breast positron emission tomography (DbPET).
METHODS
A total of 265 patients (288 tumors) underwent DbPET and contrast-enhanced magnetic resonance imaging (MRI) in a prone position. The distance between the shallowest part of the breast tumor and the front end of the pectoralis major muscle on MRI was considered as the tumor-to-chest wall distance.
RESULTS
Twenty-four tumors (8.3%) were not visualized via DbPET. The tumor-to-chest wall distance for undetectable tumors was shorter than that of the detectable tumors (23.0 mm vs 38.5 mm, P < 0.001). Multivariate analysis indicated that proximity to the chest wall and low-grade tumors were independent predicting factors for undetectable cancers. Among the 24 undetectable cancers, 15 tumors were proximal to the chest wall, suggesting that they were outside or at the edge of field of view (FOV), and 7 were low-grade tumors, suggesting insignificant F-fluorodeoxyglucose (FDG) uptake.
CONCLUSIONS
The factors of undetectable breast cancers on DbPET are classified into two types; outside or at the edge of FOV and insignificant FDG uptake.
目的
评估导致环形专用乳腺正电子发射断层扫描（DbPET）无法检测到肿瘤的因素。
方法
共有265例患者（288个肿瘤）在俯卧位接受了DbPET和对比增强磁共振成像（MRI）检查。将乳腺肿瘤最浅部位与MRI上胸大肌前端之间的距离视为肿瘤至胸壁距离。
结果
24个肿瘤（8.3%）在DbPET上未显影。不可检测肿瘤的肿瘤至胸壁距离短于可检测肿瘤（23.0毫米对38.5毫米，P<0.001）。多因素分析表明，靠近胸壁和低级别肿瘤是不可检测癌症的独立预测因素。在24个不可检测的癌症中，15个肿瘤靠近胸壁，表明它们位于视野（FOV）之外或边缘，7个是低级别肿瘤，表明氟脱氧葡萄糖（FDG）摄取不明显。
结论
DbPET上不可检测乳腺癌的因素分为两类；位于FOV之外或边缘以及FDG摄取不明显。
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