口服暴露后氧化锌纳米颗粒诱导大鼠脑内氧化DNA损伤、炎症和细胞凋亡。
Zinc Oxide Nanoparticles Induced Oxidative DNA Damage, Inflammation and Apoptosis in Rat's Brain after Oral Exposure.
作者信息
Attia Hala, Nounou Howaida, Shalaby Manal
机构信息
Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11495, Saudi Arabia.
Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
出版信息
Toxics. 2018 May 26;6(2):29. doi: 10.3390/toxics6020029.
Abstract
Growing evidences demonstrated that zinc oxide nanoparticles (ZnONPs) could reach the brain after oral ingestion; however, the "neurotoxicity of" ZnONPs after oral exposure has not been fully investigated. This study aimed to explore the "neurotoxicity of" ZnONPs (.
摘要
越来越多的证据表明，氧化锌纳米颗粒（ZnONPs）经口服后可进入大脑；然而，口服暴露后ZnONPs的“神经毒性”尚未得到充分研究。本研究旨在探讨ZnONPs的“神经毒性”（。
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