Department of Otolaryngology, Head and Neck Surgery, Zhongda Hospital, Southeast University, No. 87 Dingjiaqiao Road, Nanjing 210009, China.
Department of Otolaryngology, Head and Neck Surgery, Nanjing Drum Tower Hospital, No. 321 Zhongshan Road, Nanjing 210008, China.
Neural Plast. 2018 May 13;2018:6059697. doi: 10.1155/2018/6059697. eCollection 2018.
Tinnitus is believed to result from the maladaptive plasticity of the auditory nervous system; reports regarding its severity and prognosis are conflicting. We evaluated the characteristic and short-term prognosis of tinnitus associated with sudden sensorineural hearing loss (SSNHL). A total of 230 cases were enrolled. The severity and 1-month prognosis of tinnitus (according to the Tinnitus Handicap Inventory (THI)) were assessed in terms of the patients' sex, age, level of hearing loss, type of audiogram results, and so on. According to our statistical analysis, the degree of handicap due to tinnitus was not related to sex, age, or level of hearing loss; the Tinnitus Handicap Inventory indicated that the low-frequency-audiogram group had a low tinnitus handicap ( = 7.516, = 0.000). Furthermore, we found that the prognosis of tinnitus was not related to the type of audiogram or level of hearing loss. Recovery from a severe level of hearing loss was, however, found to be associated with a poor tinnitus prognosis ( = 5.203, = 0.006). In summary, our study indicates that the association between tinnitus and SSNHL is extremely high. Tinnitus can be ameliorated by the successful treatment of hearing loss. The study was registered in the Chinese Clinical Trial Registry (ChiCTR1800014797).
耳鸣被认为是听觉神经系统适应不良性可塑性的结果；关于其严重程度和预后的报告相互矛盾。我们评估了突发性聋（SSNHL）伴耳鸣的特征和短期预后。共纳入 230 例。根据患者的性别、年龄、听力损失程度、听阈图类型等，评估耳鸣的严重程度和 1 个月预后（根据耳鸣残疾量表（THI））。根据我们的统计分析，耳鸣引起的残疾程度与性别、年龄或听力损失程度无关；耳鸣残疾量表表明低频听阈组的耳鸣残疾程度较低（=7.516，=0.000）。此外，我们发现耳鸣的预后与听阈图类型或听力损失程度无关。然而，严重程度听力损失的恢复与较差的耳鸣预后相关（=5.203，=0.006）。综上所述，我们的研究表明耳鸣与 SSNHL 之间存在高度关联。通过成功治疗听力损失，可以改善耳鸣。该研究已在中国临床试验注册中心（ChiCTR1800014797）注册。
