Haapala Eero A, Veijalainen Aapo, Kujala Urho M, Finni Taija
Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Clin Physiol Funct Imaging. 2019 Jan;39(1):22-28. doi: 10.1111/cpf.12528. Epub 2018 Jun 3.
The aim of this study was to investigate the short-term reproducibility of aortic pulse wave velocity (PWVao) and augmentation index (AIx%) assessed by the non-invasive oscillometric device. Altogether of 55 (19 boys, 36 girls) adolescents 16-19-years-of-age participated in the study. PWVao and AIx% were measured during the same laboratory visit at 2 min intervals using the Arteriograph™ device. Peak oxygen uptake (V̇O ) was assessed by the maximal exercise test on a cycle ergometer and body fat percentage by bioelectrical impedance analysis. We studied reproducibility using intraclass correlation coefficients (ICC), coefficient variation with the root-means-square method expressed as percentages (CV%), and 95% limit of agreement (95% LA) and coefficient repeatability of the Bland-Altman plot. ICC for PWVao was 0·90, CV% 3·7 and the limits of agreement were -0·70 and 0·58 with a coefficient repeatability of 0·65. ICC for AIx% was 0·88, CV% 29·1%, and the limits of agreement were -6·8 and 7·1 with a coefficient repeatability of 6·9. No relevant differences in ICC, CV%, and coefficient repeatability for PWVao between adolescents with higher or lower V̇O or body fat percentage were observed. For AIx%, ICC was lower, CV% higher and coefficient repeatability higher in adolescents with higher V̇O or lower body fat percentage than in adolescents with lower V̇O or higher body fat percentage. Short-term reproducibility of Arteriograph™-derived PWVao was relatively good and was not affected by V̇O or adiposity. However, the reproducibility of AIx% was modest especially among adolescents with higher V̇O and lower body fat percentage.
本研究旨在探讨通过无创示波装置评估的主动脉脉搏波速度（PWVao）和增强指数（AIx%）的短期可重复性。共有55名16至19岁的青少年（19名男孩，36名女孩）参与了该研究。使用Arteriograph™设备在同一实验室就诊期间每隔2分钟测量一次PWVao和AIx%。通过在自行车测力计上进行的最大运动测试评估峰值摄氧量（V̇O ），并通过生物电阻抗分析评估体脂百分比。我们使用组内相关系数（ICC）、用均方根法表示为百分比的变异系数（CV%）、95%一致性界限（95%LA）以及Bland-Altman图的重复性系数来研究可重复性。PWVao的ICC为0·90，CV%为3·7，一致性界限为-0·70和0·58，重复性系数为0·65。AIx%的ICC为0·88，CV%为29·1%，一致性界限为-6·8和7·1，重复性系数为6·9。在V̇O 较高或较低或体脂百分比不同的青少年之间，未观察到PWVao的ICC、CV%和重复性系数存在相关差异。对于AIx%，V̇O 较高或体脂百分比较低的青少年的ICC较低，CV%较高，重复性系数较高，而V̇O 较低或体脂百分比较高的青少年则相反。Arteriograph™得出的PWVao的短期可重复性相对较好，且不受V̇O 或肥胖的影响。然而，AIx%的可重复性一般，尤其是在V̇O 较高且体脂百分比较低的青少年中。
