Veri Kadi, Talvik Inga, Vaher Ulvi, Napa Aita, Ilves Pilvi, Uibo Oivi, Õiglane-Shlik Eve, Laugesaar Rael, Rein Reet, Kolk Anneli, Noormets Klari, Reimand Tiia, Õunap Katrin, Talvik Tiina
1 Department of Pediatrics, University of Tartu, Tartu, Estonia.
2 Tallinn Children's Hospital, Tallinn, Estonia.
J Child Neurol. 2018 Aug;33(9):587-592. doi: 10.1177/0883073818776760. Epub 2018 Jun 4.
The aim of this prospective epidemiological study was to establish the incidence rate of childhood epilepsy in Estonia, to describe the clinical spectrum and to identify etiology of childhood epilepsy. The overall incidence rate was 86.3/100 000. The incidence rate was the highest (141.9/100 000) in the age group from 5 to 9 years. Specific electroclinical syndromes were identified in 22.8% of cases. Structural or metabolic etiology was identified in 20.0% of cases, presumed genetic origin was identified in 33.9% of cases, and in 46.1% of cases the cause of epilepsy remained unknown. The incidence rate of childhood epilepsy in Estonia (86.3/100 000) is similar to the other European countries. In comparison with the results of the first epidemiological study of childhood epilepsy in Estonia (incidence rate 45/100 000; Beilmann et al), the incidence rate in this study is almost 2 times higher, what can be explained with better case collection and improved diagnostic modalities in Estonia.
这项前瞻性流行病学研究的目的是确定爱沙尼亚儿童癫痫的发病率，描述其临床谱并确定儿童癫痫的病因。总体发病率为86.3/10万。5至9岁年龄组的发病率最高（141.9/10万）。22.8%的病例确定了特定的电临床综合征。20.0%的病例确定了结构性或代谢性病因，33.9%的病例确定了推测的遗传起源，46.1%的病例癫痫病因仍不明。爱沙尼亚儿童癫痫的发病率（86.3/10万）与其他欧洲国家相似。与爱沙尼亚首次儿童癫痫流行病学研究结果（发病率45/10万；Beilmann等人）相比，本研究的发病率几乎高出2倍，这可以用爱沙尼亚更好的病例收集和改进的诊断方式来解释。
