Rudroff Thorsten, Proessl Felix
Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, United States.
Department of Radiology, University of Colorado School of Medicine, Aurora, CO, United States.
Front Physiol. 2018 May 15;9:531. doi: 10.3389/fphys.2018.00531. eCollection 2018.
People with MS (PwMS) often have a more- and less-affected side of the body which results in a variety of asymmetries, including measures of power, strength, muscle activity, and limb loading. Though many studies have identified asymmetries, their impact on gait and balance in PwMS is currently unclear. In this mini-review we first summarize previous findings of asymmetries in muscle function and limb loading and their impact on gait and balance in PwMS. We then provide potential explanations for this lack of consistency in the current literature, and propose study guidelines to improve future lower limb asymmetry studies. Making use of a unified approach to study lower limb asymmetry may then provide more clarity regarding their impact on mobility, specifically gait and balance, in PwMS.
患有多发性硬化症的人（PwMS）身体通常有一侧受影响程度较高，另一侧受影响程度较低，这导致了各种不对称情况，包括力量、强度、肌肉活动和肢体负荷等方面的测量结果。尽管许多研究已经确定了不对称情况，但目前尚不清楚它们对PwMS患者步态和平衡的影响。在本综述中，我们首先总结了先前关于肌肉功能和肢体负荷不对称及其对PwMS患者步态和平衡影响的研究结果。然后，我们对当前文献中这种缺乏一致性的情况提供了潜在的解释，并提出了研究指南，以改进未来关于下肢不对称的研究。采用统一的方法来研究下肢不对称，可能会更清楚地了解它们对PwMS患者运动能力，特别是步态和平衡的影响。
