Hossain N, Akter Q M, Banu F, Mahmud S
Bangladesh Med Res Counc Bull. 2015 Dec;41(3):131-137. doi: 10.3329/bmrcb.v41i3.29970.
Cervical cancer is the main cause of malignancy-related death among women living in developing countries. The aim of this study is to evaluate the quality of life (QOL) among Bangladeshi cervical cancer survivors and its relationships with demographic and disease related factors A cross-sectional study was carried out onlone hundred nine consecutive cervical cancer survivors in National Institute of cancer Research and Hospital, Dhaka from September 2014 to february 2015 using European organization-for Research and treatment of cancer core Questionnaires (QOL-C30 and QOL- CX24). Demographic condition like education level, occupation and disease related factors like stages, treatment modality and duration of follow-up time were taken as investigating factors against functional scales. Cronbach's alpha was calculated to asses' internal consistency among items. Cervical cancer survivors stated a moderate QOL. Sub-domains of QOL score and global health status were significantly associated with physical function(PF) scales (p=.000), fatigue (p=.045), nausea and vomiting (p=.000), Appetite loss (p=.001), constipation (p=.005), symptom experience (p=.005) and menopausal symptoms (p=.015). QOL mean score were negatively associated with emotional function(EF) scales, pain, fatigue, nausea, appetite loss and financial problems. Education level showed significant association with physical function(PF) (p=.001), emotional function(EF) (p=.027), Cognitive function(CF) (p=.000) and sexual function (p=.001). Duration (Follow-up) time was significance association with PF (p=.005), EF (p=.012), symptoms experience (p=.001). Although, the QOL in cervical cancer survivors was moderate, treatment of related symptoms and improvement of demographic condition can influence the QOL and survivors improve the care of cervical cancer. So, improve the QOL among cervical cancer survivors.
宫颈癌是发展中国家女性恶性肿瘤相关死亡的主要原因。本研究旨在评估孟加拉国宫颈癌幸存者的生活质量（QOL）及其与人口统计学和疾病相关因素的关系。2014年9月至2015年2月，在达卡国立癌症研究与医院对109例连续的宫颈癌幸存者进行了一项横断面研究，使用欧洲癌症研究与治疗组织核心问卷（QOL-C30和QOL-CX24）。将教育程度、职业等人口统计学状况以及分期、治疗方式和随访时间等疾病相关因素作为针对功能量表的调查因素。计算克朗巴哈系数以评估项目间的内部一致性。宫颈癌幸存者的生活质量为中等水平。生活质量评分的子领域和总体健康状况与身体功能（PF）量表（p = .000）、疲劳（p = .045）、恶心和呕吐（p = .000）、食欲减退（p = .001）、便秘（p = .005）、症状体验（p = .005）和更年期症状（p = .015）显著相关。生活质量平均得分与情感功能（EF）量表、疼痛、疲劳、恶心、食欲减退和经济问题呈负相关。教育程度与身体功能（PF）（p = .001）、情感功能（EF）（p = .027）、认知功能（CF）（p = .000）和性功能（p = .001）显示出显著相关性。随访时间与PF（p = .005）、EF（p = .012）、症状体验（p = .001）有显著相关性。尽管宫颈癌幸存者的生活质量为中等水平，但相关症状的治疗和人口统计学状况的改善可影响生活质量，幸存者可改善宫颈癌的护理。因此，提高宫颈癌幸存者的生活质量。
