阻塞性睡眠呼吸暂停与2型糖尿病
Obstructive Sleep Apnoea and Type 2 Diabetes.
作者信息
Tahrani Abd A, Ali Asad
机构信息
NIHR Clinician Scientist, Centre of Endocrinology, Diabetes and Metabolism, University of Birmingham and Honorary Consultant Physician, Department of Diabetes and Endocrinology, Heart of England NHS Foundation Trust, Birmingham, UK.
Consultant Respiratory Physician, Department of Respiratory Medicine, University Hospital of Coventry and Warwickshire, Coventry, UK.
出版信息
Eur Endocrinol. 2014 Feb;10(1):43-50. doi: 10.17925/EE.2014.10.01.43. Epub 2014 Feb 28.
With the growing prevalence of obesity, the burden of type 2 diabetes is increasing. Obstructive sleep apnoea (OSA) is a very common medical condition that is associated with increased risk of cardiovascular disease and mortality. Obesity is a common risk factor for OSA and type 2 diabetes and hence it is not surprising that OSA and type 2 diabetes are interlinked. OSA has been shown to be an independent risk factor for the development of incident pre-diabetes/type 2 diabetes. OSA is also associated with worse glycaemic control and vascular disease in patients with type 2 diabetes. However, evidence for the benefits of OSA treatment in patients with type 2 diabetes is still lacking. The aim of this article is to provide an overview of OSA, the relationships between OSA and dysglycaemia and the impact of OSA in patients with type 2 diabetes, highlighting recent advances in the field.
随着肥胖症患病率的不断上升，2型糖尿病的负担也在增加。阻塞性睡眠呼吸暂停（OSA）是一种非常常见的病症，与心血管疾病风险增加和死亡率相关。肥胖是OSA和2型糖尿病的常见危险因素，因此OSA和2型糖尿病相互关联并不奇怪。OSA已被证明是新发糖尿病前期/2型糖尿病发生的独立危险因素。OSA还与2型糖尿病患者的血糖控制不佳和血管疾病有关。然而，仍缺乏OSA治疗对2型糖尿病患者有益的证据。本文旨在概述OSA、OSA与血糖异常之间的关系以及OSA对2型糖尿病患者的影响，突出该领域的最新进展。
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