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成人痤疮的维持治疗重要吗?用阿达帕林、低剂量 α-羟酸和 β-羟酸进行维持治疗可带来益处。

Is maintenance treatment in adult acne important? Benefits from maintenance therapy with adapalene, and low doses of alpha and beta hydroxy acids.

机构信息

a Nova Derm Dermatology Centre , Warsaw , Poland.

b Department of Quantitative Finance, Faculty of Economic Sciences, University of Warsaw , Warsaw , Poland.

出版信息

J Dermatolog Treat. 2019 Sep;30(6):568-571. doi: 10.1080/09546634.2018.1484874. Epub 2019 Apr 11.

DOI:10.1080/09546634.2018.1484874
PMID:29873567
Abstract

Adult acne is a chronic disease with uncontrolled exacerbations, associated with a psychological burden of the patient and medical expenses. The aim of the study was to check the efficacy of maintenance therapy of adult acne. It is essential part of treatment as adult acne usually has a long-lasting and recurring course. In the study, the efficacy of maintenance therapy in patients with adult acne is evaluated. In this study, 100 patients (aged 25-39 years of age) with mild and moderate adult acne were enrolled. The maintenance therapy (adapalene 0.1% three times a week and low doses of alpha and beta hydroxy acids) led to a significant decrease in the number of acne lesions (from 31.3 to 12.25;  < .001) and severity of seborrhea ( < .001). Maintenance therapy brings significant improvements in the reduction of non-inflammatory and inflammatory lesions in patients with mild and moderate adult acne.

摘要

成人痤疮是一种慢性疾病,伴有反复发作,给患者带来心理负担和医疗费用。本研究的目的是检查成人痤疮维持治疗的疗效。作为治疗的重要组成部分,因为成人痤疮通常具有持久和反复发作的过程。在这项研究中,评估了成人痤疮患者维持治疗的疗效。在这项研究中,纳入了 100 名(年龄 25-39 岁)患有轻度和中度成人痤疮的患者。维持治疗(阿达帕林 0.1%,每周三次和低剂量的α和β羟基酸)导致痤疮病变数量显著减少(从 31.3 减少到 12.25; < .001)和皮脂溢严重程度降低( < .001)。维持治疗可显著改善轻度和中度成人痤疮患者非炎症和炎症病变的减少。

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