Wang Xiaohong, Liu Jinfeng, Wang Peizhou, deMello Andrew, Feng Lingyan, Zhu Xiaoli, Wen Weijia, Kodzius Rimantas, Gong Xiuqing
Materials Genome Institute, Shanghai University, Shanghai 201800, China.
Advanced Placement of Chemistry Program, International Department, Huzhou New Century Foreign Language School, Huzhou 313100, China.
Genes (Basel). 2018 Jun 5;9(6):283. doi: 10.3390/genes9060283.
Recently, microfluidic technologies have attracted an enormous amount of interest as potential new tools for a large range of applications including materials synthesis, chemical and biological detection, drug delivery and screening, point-of-care diagnostics, and in-the-field analysis. Their ability to handle extremely small volumes of fluids is accompanied by additional benefits, most notably, rapid and efficient mass and heat transfer. In addition, reactions performed within microfluidic systems are highly controlled, meaning that many advanced materials, with uniform and bespoke properties, can be synthesized in a direct and rapid manner. In this review, we discuss the utility of microfluidic systems in the synthesis of materials for a variety of biological applications. Such materials include microparticles or microcapsules for drug delivery, nanoscale materials for medicine or cellular assays, and micro- or nanofibers for tissue engineering.
近年来，微流控技术作为一系列潜在的新工具，在包括材料合成、化学和生物检测、药物递送与筛选、即时诊断以及现场分析等广泛应用领域引起了极大关注。它们处理极少量流体的能力还带来了其他优势，最显著的是快速高效的质量和热传递。此外，在微流控系统内进行的反应受到高度控制，这意味着许多具有均匀且定制特性的先进材料能够以直接且快速的方式合成。在本综述中，我们讨论微流控系统在合成用于各种生物应用的材料方面的效用。此类材料包括用于药物递送的微粒或微胶囊、用于医学或细胞分析的纳米级材料以及用于组织工程的微纤维或纳米纤维。
