一种新的黎巴嫩药物依从性量表：在黎巴嫩高血压成年人中的验证
A New Lebanese Medication Adherence Scale: Validation in Lebanese Hypertensive Adults.
作者信息
Bou Serhal R, Salameh P, Wakim N, Issa C, Kassem B, Abou Jaoude L, Saleh N
机构信息
Department of Epidemiology and biostatistics, Faculty of Public Health, Lebanese University, Fanar, Lebanon.
Faculty of Pharmacy, Lebanese University, Al Hadath, Lebanon.
出版信息
Int J Hypertens. 2018 May 20;2018:3934296. doi: 10.1155/2018/3934296. eCollection 2018.
BACKGROUND
A new Lebanese scale measuring medication adherence considered socioeconomic and cultural factors not taken into account by the eight-item Morisky Medication Adherence Scale (MMAS-8). were to validate the new adherence scale and its prediction of hypertension control, compared to MMAS-8, and to assess adherence rates and factors.
METHODOLOGY
A cross-sectional study, including 405 patients, was performed in outpatient cardiology clinics of three hospitals in Beirut. Blood pressure was measured, a questionnaire filled, and sodium intake estimated by a urine test. Logistic regression defined predictors of hypertension control and adherence.
RESULTS
54.9% had controlled hypertension. 82.4% were adherent by the new scale, which showed good internal consistency, adequate questions (KMO coefficient = 0.743), and four factors. It predicted hypertension control (OR = 1.217; value = 0.003), unlike MMAS-8, but the scores were correlated (ICC average measure = 0.651; value < 0.001). Stress and smoking predicted nonadherence.
CONCLUSION
This study elaborated a validated, practical, and useful tool measuring adherence to medications in Lebanese hypertensive patients.
背景
一种新的黎巴嫩药物依从性量表考虑了社会经济和文化因素，而八项Morisky药物依从性量表（MMAS - 8）未考虑这些因素。旨在验证新的依从性量表及其对高血压控制的预测能力，并与MMAS - 8进行比较，同时评估依从率和相关因素。
方法
在贝鲁特三家医院的门诊心脏病诊所进行了一项横断面研究，纳入405名患者。测量血压、填写问卷，并通过尿液检测估算钠摄入量。采用逻辑回归确定高血压控制和依从性的预测因素。
结果
54.9%的患者高血压得到控制。新量表显示82.4%的患者依从，该量表具有良好的内部一致性、合适的问题（KMO系数 = 0.743）以及四个因素。与MMAS - 8不同，它能预测高血压控制情况（OR = 1.217；P值 = 0.003），但两者得分具有相关性（组内相关系数平均测量值 = 0.651；P值 < 0.001）。压力和吸烟是不依从的预测因素。
结论
本研究精心设计了一种经过验证的、实用且有用的工具，用于测量黎巴嫩高血压患者的药物依从性。
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