• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

耳前区坏疽性脓皮病合并溃疡性结肠炎:一例报告及文献复习

Pyoderma Gangrenosum of the Preauricular Area with Ulcerative Colitis: A Case Report and Review.

作者信息

Chae Hee Sung, Han Sung Min, Lee Ha Neul, Jeon Hyun Jong, Seo Young Joon

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Wonju Severance Christian Hospital, Yonsei University College of Medicine, Wonju, Korea.

出版信息

J Audiol Otol. 2018 Oct;22(4):248-252. doi: 10.7874/jao.2018.00171. Epub 2018 Jun 14.

DOI:10.7874/jao.2018.00171
PMID:29890815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6233936/
Abstract

Pyoderma gangrenosum (PG) is primarily, a sterile, inflammatory, neutrophilic dermatosis, characterized by recurrent cutaneous ulceration with mucopurulent or hemorrhagic exudate. The incidence of PG is uncertain, but it is estimated to be about 3-10 patients per million per year. It occurs most commonly on the lower legs, but has been reported at other sites of the body as well. The causes of PG are unknown, but about 50-70% of cases are associated with other diseases, mainly inflammatory bowel disease. We hereby report a case of PG in a 21-year-old male, with a history of ulcerative colitis (UC). After appropriate diagnostic methods including biopsy for pathologic confirmation, sigmoidoscopy and computed tomography, we excluded other diseases and the lesion was diagnosed as PG. We then carried out regular dressing of the wound, while UC was treated with steroid and immunosuppressant medication, with inputs from the department of gastroenterology during the hospital stay. There occurred recurrence of the skin lesion, 7 months after discharge, after which they improved. UC has been in the remission state as per the follow-up, since 2 years.

摘要

坏疽性脓皮病(PG)主要是一种无菌性、炎症性、嗜中性皮病,其特征为皮肤反复溃疡并伴有黏液脓性或血性渗出物。PG的发病率尚不确定,但估计约为每年每百万人中有3至10例患者。它最常发生于小腿,但也有在身体其他部位出现的报道。PG的病因不明,但约50%至70%的病例与其他疾病相关,主要是炎症性肠病。我们在此报告一例21岁男性的PG病例,该患者有溃疡性结肠炎(UC)病史。经过包括活检进行病理确诊、乙状结肠镜检查和计算机断层扫描等适当的诊断方法后,我们排除了其他疾病,该病变被诊断为PG。然后我们对伤口进行了定期换药,同时UC采用类固醇和免疫抑制药物治疗,住院期间有胃肠病科参与。出院7个月后皮肤病变复发,之后有所改善。根据随访情况,UC自两年以来一直处于缓解状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/2a7bae2255b0/jao-2018-00171f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/24257395b4cf/jao-2018-00171f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/b9de7bd569ae/jao-2018-00171f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/c335c53fc0c3/jao-2018-00171f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/1734a4576519/jao-2018-00171f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/2a7bae2255b0/jao-2018-00171f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/24257395b4cf/jao-2018-00171f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/b9de7bd569ae/jao-2018-00171f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/c335c53fc0c3/jao-2018-00171f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/1734a4576519/jao-2018-00171f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bf0/6233936/2a7bae2255b0/jao-2018-00171f5.jpg

相似文献

1
Pyoderma Gangrenosum of the Preauricular Area with Ulcerative Colitis: A Case Report and Review.耳前区坏疽性脓皮病合并溃疡性结肠炎:一例报告及文献复习
J Audiol Otol. 2018 Oct;22(4):248-252. doi: 10.7874/jao.2018.00171. Epub 2018 Jun 14.
2
Generalized Pyoderma Gangrenosum Associated with Ulcerative Colitis: Successful Treatment with Infliximab and Azathioprine.与溃疡性结肠炎相关的泛发性坏疽性脓皮病:英夫利昔单抗和硫唑嘌呤治疗成功
Acta Dermatovenerol Croat. 2016 Apr;24(1):83-5.
3
A case of pyoderma gangrenosum with ulcerative colitis treated with mesalazine.1例用美沙拉嗪治疗的坏疽性脓皮病合并溃疡性结肠炎患者。
Ann Dermatol. 2010 Nov;22(4):422-5. doi: 10.5021/ad.2010.22.4.422. Epub 2010 Nov 5.
4
Coexistence of pyoderma gangrenosum and sweet's syndrome in a patient with ulcerative colitis.一名溃疡性结肠炎患者同时患有坏疽性脓皮病和斯威特综合征。
Pan Afr Med J. 2015 Jun 24;21:151. doi: 10.11604/pamj.2015.21.151.6364. eCollection 2015.
5
Narrative Review: Pyoderma Gangrenosum.叙述性综述:坏疽性脓皮病
Cureus. 2024 Jan 7;16(1):e51805. doi: 10.7759/cureus.51805. eCollection 2024 Jan.
6
[Ulcerative colitis diagnosed with facial pyoderma gangrenosum: a case report].[面部坏疽性脓皮病诊断为溃疡性结肠炎:一例报告]
Nihon Shokakibyo Gakkai Zasshi. 2024;121(6):481-488. doi: 10.11405/nisshoshi.121.481.
7
Pyoderma gangrenosum in a renal transplant recipient: A case report and review of literature.肾移植受者的坏疽性脓皮病:一例病例报告及文献综述
Indian J Nephrol. 2015 Sep-Oct;25(5):297-9. doi: 10.4103/0971-4065.156900.
8
Ulcerative Colitis Diagnosed through Evaluation of Underlying Diseases in a Pyoderma Gangrenosum Adolescent without Gastrointestinal Symptoms.通过对一名无胃肠道症状的坏疽性脓皮病青少年潜在疾病的评估诊断出溃疡性结肠炎。
Ann Dermatol. 2023 Nov;35(Suppl 2):S292-S295. doi: 10.5021/ad.22.101.
9
Colocutaneous fistula through ulcerative colitis and cancer to the pyoderma gangrenosum: a never-ending story for a single patient. Case report.经溃疡性结肠炎和癌症至坏疽性脓皮病的结肠皮肤瘘:一位患者的无尽故事。病例报告。
G Chir. 2019 Jan-Feb;40(1):39-43.
10
[Ulcerative colitis complicated by pyoderma gangrenosum and multiple aseptic abscesses].[溃疡性结肠炎合并坏疽性脓皮病及多发性无菌性脓肿]
Nihon Shokakibyo Gakkai Zasshi. 2022;119(11):1014-1021. doi: 10.11405/nisshoshi.119.1014.

引用本文的文献

1
Pyoderma Gangrenosum as a Presenting Feature of Undifferentiated Spondyloarthropathy with Erosive Inflammatory Arthritis.坏疽性脓皮病作为未分化脊柱关节炎伴侵蚀性炎症性关节炎的首发表现
Case Rep Rheumatol. 2020 Mar 26;2020:1848562. doi: 10.1155/2020/1848562. eCollection 2020.

本文引用的文献

1
Oral Pyoderma Gangrenosum: Diagnosis, Treatment and Challenges: A Systematic Review.口腔坏疽性脓皮病:诊断、治疗及挑战:一项系统综述
Head Neck Pathol. 2017 Dec;11(4):427-441. doi: 10.1007/s12105-017-0804-3. Epub 2017 Mar 8.
2
A case of pyoderma gangrenosum with ulcerative colitis treated with mesalazine.1例用美沙拉嗪治疗的坏疽性脓皮病合并溃疡性结肠炎患者。
Ann Dermatol. 2010 Nov;22(4):422-5. doi: 10.5021/ad.2010.22.4.422. Epub 2010 Nov 5.
3
Pustular pyoderma gangrenosum: an uncommon variant which is easily misdiagnosed.脓疱型坏疽性脓皮病:一种易被误诊的罕见变异型。
Dermatol Online J. 2008 Feb 28;14(2):21.
4
Pyoderma gangrenosum in the head and neck.头颈部坏疽性脓皮病
Arch Otolaryngol Head Neck Surg. 2007 Jan;133(1):83-5. doi: 10.1001/archotol.133.1.83.
5
Pyoderma gangrenosum associated with ulcerative colitis: response to infliximab.与溃疡性结肠炎相关的坏疽性脓皮病:对英夫利昔单抗的反应
Rev Esp Enferm Dig. 2004 Jun;96(6):420-2; 422-4. doi: 10.4321/s1130-01082004000600008.
6
Pyoderma gangrenosum in association with chronic ulcerative colitis.坏疽性脓皮病与慢性溃疡性结肠炎相关。
Ohio State Med J. 1954 Dec;50(12):1150-1.
7
Pyoderma gangrenosum: a review.坏疽性脓皮病:综述
J Cutan Pathol. 2003 Feb;30(2):97-107. doi: 10.1034/j.1600-0560.2003.00024.x.
8
Pyoderma gangrenosum of the scalp treated with cyclosporine A.头皮坏疽性脓皮病采用环孢素A治疗。
Int J Dermatol. 2002 Dec;41(12):916-8. doi: 10.1046/j.1365-4362.2002.01680_3.x.
9
The glucagonoma syndrome: a review of its features and discussion of new perspectives.
Am J Med Sci. 2001 May;321(5):306-20. doi: 10.1097/00000441-200105000-00003.
10
Immune-related systemic manifestations of inflammatory bowel disease. A prospective study of 792 patients.
J Clin Gastroenterol. 1996 Jul;23(1):29-34. doi: 10.1097/00004836-199607000-00009.