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2002 年至 2016 年心血管疾病和高血压趋势分析:减盐策略实施后。

Cardiovascular disease and high blood pressure trend analyses from 2002 to 2016: after the implementation of a salt reduction strategy.

机构信息

Escola Nacional de Saúde Pública, Universidade Nova de Lisboa, Avenida Padre Cruz, 1600-560, Lisboa, Portugal.

Centro de Investigação em Saúde Pública - ENSP-UNL, Avenida Padre Cruz, 1600-560, Lisboa, Portugal.

出版信息

BMC Public Health. 2018 Jun 11;18(1):722. doi: 10.1186/s12889-018-5634-z.

Abstract

BACKGROUND

Cardiovascular disease (CVD) is the leading cause of death around the world; however, many CVD events could be prevented if we focused on modification of the main risk factors. Increased salt consumption is estimated to have caused millions of deaths, mostly related to CVD, particularly stroke, which is the leading cause of death in Portugal. In our study, we aim to assess trends in the proportion of high blood pressure (HBP) in Acute Coronary Syndrome (ACS) patients as well as the trends in stroke and ACS in Portugal, especially after a set of public health initiatives were implemented to reduce salt intake.

METHODS

The monthly proportion of ACS patients presenting with previously diagnosed HBP and the monthly rate of CVD admissions into public hospitals in Portugal were calculated. CVD rates were stratified into ACS rate and stroke rates. Data were stratified by demographics variables. An interrupted time-series model was used to assess changes over time.

RESULTS

Breakpoint analysis revealed an estimated breakpoint around the year 2013 for the proportion of HBP patients, the following year there was a decreasing trend, however it was not significant. Analyses showed the trend before 2013 was increasing and started to decrease after this year. This decreased in proportion of HBP patients can be translated into a reduction of 555 people per year presenting with HBP in the ACS population. We analysed trends for ACS and stroke and tested the significance for a breakpoint in the year 2013. Although none of the remaining trends were significant for ACS crude rates and stroke crude rate, a decreasing trend was observed.

CONCLUSIONS

This research provides an indication about the impact a population-wide approach to CVD risk factors has on CVD trends themselves. Our results suggest that population-wide approaches can have an impact on the prevention and improvement of CVD control, reducing the number of CVD events, and eventually reducing premature death by CVD. As more restrictions on salt intake are being planned in Portugal in the next years, it is highly relevant to assess what is the current panorama and what further reductions we can expect.

摘要

背景

心血管疾病(CVD)是全球范围内的主要死亡原因;然而,如果我们专注于主要危险因素的改变,许多 CVD 事件是可以预防的。据估计,盐摄入量的增加导致了数百万人死亡,其中大部分与 CVD 有关,尤其是中风,这是葡萄牙的主要死亡原因。在我们的研究中,我们旨在评估急性冠状动脉综合征(ACS)患者中高血压(HBP)比例的趋势,以及葡萄牙中风和 ACS 的趋势,特别是在实施了一系列减少盐摄入量的公共卫生举措之后。

方法

计算每月 ACS 患者中先前诊断为 HBP 的比例以及葡萄牙公立医院 CVD 入院人数的月度比率。CVD 发病率分为 ACS 发病率和中风发病率。数据按人口统计学变量分层。使用中断时间序列模型评估随时间的变化。

结果

断点分析显示,HBP 患者比例的估计断点约在 2013 年左右,次年呈下降趋势,但不显著。分析表明,2013 年前的趋势是上升的,并且在这一年之后开始下降。HBP 患者比例的下降可以转化为每年在 ACS 人群中减少 555 名患有 HBP 的人。我们分析了 ACS 和中风的趋势,并测试了 2013 年的断点是否显著。尽管 ACS 粗发病率和中风粗发病率的其余趋势均不显著,但观察到下降趋势。

结论

这项研究提供了关于人群方法对 CVD 危险因素的影响的指示,从而对 CVD 趋势本身产生影响。我们的结果表明,人群方法可以对 CVD 的预防和改善产生影响,从而减少 CVD 事件的发生,并最终减少 CVD 导致的过早死亡。由于葡萄牙计划在未来几年对盐摄入量进行更多限制,因此评估当前的情况以及可以预期的进一步减少是非常重要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f360/5996516/cbbf5971ca3b/12889_2018_5634_Fig1_HTML.jpg

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