Nadar Sunil K, Tariq Osama
Sultan Qaboos University Hospital Muscat, Oman.
Card Fail Rev. 2018 May;4(1):6-8. doi: 10.15420/cfr.2018:7:2.
Since the publication of European Society of Cardiology guidelines for the diagnosis and treatment of acute and chronic heart failure (HF) in 2016, a new class of HF has been defined, namely HF with mildly reduced ejection fraction (HFmrEF). Although the name was new, there had long been awareness of the existence of a grey area between the two established classes of HF: HF with reduced ejection fraction and HF with preserved ejection fraction. Patients between these two classes were previously either excluded from HF studies or were included in the other groups. With the definition of this new group of patients, a door has opened for researchers to further explore their characteristics, treatment and outcomes. In this article we aim to clarify the existing literature on the clinical characteristics and pathophysiology of this newly-defined group of patients.
自欧洲心脏病学会于2016年发布急性和慢性心力衰竭（HF）诊断与治疗指南以来，已定义了一类新的心力衰竭，即射血分数轻度降低的心力衰竭（HFmrEF）。尽管这个名称是新的，但人们早就意识到，在已确立的两类心力衰竭之间存在一个灰色地带：射血分数降低的心力衰竭和射血分数保留的心力衰竭。这两类之间的患者以前要么被排除在心力衰竭研究之外，要么被纳入其他组。随着这一新患者群体的定义，为研究人员进一步探索他们的特征、治疗和预后打开了一扇门。在本文中，我们旨在阐明关于这一新定义患者群体的临床特征和病理生理学的现有文献。
