Buisine Nicolas, Kerdivel Gwenneg, Sachs Laurent M
Function and Mechanism of Action of Thyroid Hormone Receptor group, UMR 7221 CNRS and Muséum National d'Histoire Naturelle, Sorbonne Universités, Paris, France.
Methods Mol Biol. 2018;1801:265-285. doi: 10.1007/978-1-4939-7902-8_21.
Thyroid hormones are pleiotropic hormones involved in chordates physiology. Understanding their functions and mechanisms is also instrumental to diagnose dys-regulations and get a predictive power that can applied to medicine, ecology, etc. Today, high-throughput sequencing technologies offer the opportunity to address this issue not only in model organisms but also in non-model organisms. Here, we describe a method that makes use of RNA-seq to address differential expression analysis in non-model organism.
甲状腺激素是参与脊索动物生理学的多效性激素。了解它们的功能和机制对于诊断失调情况以及获得可应用于医学、生态学等领域的预测能力也很有帮助。如今，高通量测序技术不仅为在模式生物中，也为在非模式生物中解决这一问题提供了机会。在此，我们描述一种利用RNA测序来进行非模式生物差异表达分析的方法。
