Yasuda Ryu, Minami Kisei, Ogawa Akira, Okada Hideshi, Terakawa Runa, Koike Yumi, Ogura Shinji, Takeuchi Kouichi, Higuchi Tsukasa
Department of General Pediatrics, Nagano Children's Hospital, Nagano, Japan.
Department of Emergency and Disaster Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
J Med Case Rep. 2019 Jun 15;13(1):182. doi: 10.1186/s13256-019-2082-z.
Development of neurological complications of varicella zoster virus reactivation is relatively uncommon, particularly in an immunocompetent child.
An 11-year-old Asian girl presented with headache and skin rash on her left chest. She was diagnosed with meningitis, and herpes zoster was confirmed by polymerase chain reaction using cerebrospinal fluid. Acyclovir was administered intravenously. Given the favorable evolution of the clinical course, she was discharged from the hospital on day 8 of her illness. She had no apparent sequelae or comorbidities at the time of the 6-week follow-up.
Neurological complications such as meningitis due to varicella zoster virus reactivation are uncommon, especially in an immunocompetent child; no specific immune deficiency was identified in our patient. We conclude that, although rare, varicella zoster virus should be recognized as a potential cause of viral meningitis in immunocompetent children.
水痘带状疱疹病毒再激活引发神经并发症的情况相对少见，尤其是在免疫功能正常的儿童中。
一名11岁亚洲女孩出现头痛及左胸皮肤皮疹。她被诊断为脑膜炎，通过脑脊液聚合酶链反应确诊为带状疱疹。给予静脉注射阿昔洛韦。鉴于临床病程进展良好，她在患病第8天出院。在6周随访时，她没有明显的后遗症或合并症。
水痘带状疱疹病毒再激活引起的诸如脑膜炎等神经并发症并不常见，特别是在免疫功能正常的儿童中；我们的患者未发现特定的免疫缺陷。我们得出结论，尽管罕见，但水痘带状疱疹病毒应被视为免疫功能正常儿童病毒性脑膜炎的潜在病因。
