Suzuki Akiko, Jun Goo, Abdallah Nada, Gajera Mona, Iwata Junichi
Department of Diagnostic & Biomedical Sciences, School of Dentistry, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Center for Craniofacial Research, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Data Brief. 2018 Mar 14;18:655-673. doi: 10.1016/j.dib.2018.03.010. eCollection 2018 Jun.
This article presents data on genes associated with cleft palate (CP), retrieved through both a full-text systematic review and a mouse genome informatics (MGI) database search. In order to group CP-associated genes according to function, pathway, biological process, and cellular component, the genes were analyzed using category enrichment bioinformatics tools, the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO). This approach provides invaluable opportunities for the identification of candidate pathways and genes in CP research.
本文展示了通过全文系统综述和小鼠基因组信息学(MGI)数据库检索获得的与腭裂(CP)相关的基因数据。为了根据功能、通路、生物学过程和细胞成分对CP相关基因进行分组,使用了类别富集生物信息学工具、京都基因与基因组百科全书(KEGG)和基因本体论(GO)对这些基因进行分析。这种方法为腭裂研究中候选通路和基因的识别提供了宝贵的机会。