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在果蝇核糖体DNA基因单元中发现的一种新的类copia转座元件。

A new copia-like transposable element found in a Drosophila rDNA gene unit.

作者信息

Bell J R, Bogardus A M, Schmidt T, Pellegrini M

出版信息

Nucleic Acids Res. 1985 Jun 11;13(11):3861-71. doi: 10.1093/nar/13.11.3861.

Abstract

We have discovered a member of a new family of copia-like transposable elements inserted into the non-transcribed spacer between two ribosomal genes (rDNA). This family, which we call 3S18, consists of at least 15 elements which are scattered throughout the Drosophila melanogaster genome. The elements of this family are approximately 6.5 kb long and have 0.5 kb terminal direct repeats. All of the elements appear to have the same restriction sites. The element is mobile as the size pattern of homologous fragments varies among different strains. In situ hybridization results confirm the scattered location and transposable qualities of 3S18. The element is not transcribed into abundant RNA.

摘要

我们发现了一个类copia转座元件新家族的一个成员,它插入到两个核糖体基因(rDNA)之间的非转录间隔区。这个家族,我们称之为3S18,由至少15个元件组成,它们散布在黑腹果蝇的整个基因组中。这个家族的元件大约6.5 kb长,有0.5 kb的末端正向重复序列。所有元件似乎都有相同的限制酶切位点。由于同源片段的大小模式在不同菌株间有所不同,所以该元件是可移动 的。原位杂交结果证实了3S18的散布位置和转座特性。该元件不会转录成大量RNA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e35/341282/2d72abae4c38/nar00305-0086-a.jpg

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