Department of Social Sciences of Physical Activity, Sports and Leisure, Faculty of Sciences for Physical Activity and Sport, INEF, Technical University of Madrid (UPM), Madrid, Spain.
Department of Obstetrics and Gynecology, University Hospital of Torrejon, Madrid, Spain.
Br J Sports Med. 2019 Mar;53(6):348-353. doi: 10.1136/bjsports-2017-098926. Epub 2018 Jun 13.
The incidence of depression is high during the perinatal period. This mood disorder can have a significant impact on the mother, the child and the family.
To examine the effect of an exercise programme during pregnancy on the risk of perinatal depression.
Healthy women who were <16 weeks pregnant were randomly assigned to two different groups. Women in the intervention group participated in a 60 min exercise programme throughout pregnancy, 3 days per week, which was conducted from October 2014 to December 2016. The Center for Epidemiological Studies-Depression Scale was used to measure the risk of depression at the beginning of the study (12-16 weeks), at gestational week 38 and at 6 weeks postpartum.
One hundred and twenty-four pregnant women were allocated to either the intervention (IG=70) or the control (CG=54) group. No differences were found in the percentage of depressed women at baseline (20% vs 18.5%) (χ2=0.043; p=0.836). A smaller percentage of depressed women were identified in the IG compared with the CG at 38 gestational weeks (18.6% vs 35.6%) (χ2=4.190; p=0.041) and at 6 weeks postpartum (14.5% vs 29.8%) (χ2=3.985; p=0.046) using the per-protocol analysis. No significant differences were found using the intention-to-treat analyses, except in the multiple imputation analysis at week 38 (18.6% vs 34.4%) (χ2=4.085; p=0.049).
An exercise programme performed during pregnancy may reduce the prevalence of depression in late pregnancy and postpartum.
NCT02420288; Results.
围产期抑郁症的发病率很高。这种情绪障碍会对母亲、孩子和家庭产生重大影响。
研究孕期运动方案对围产期抑郁症风险的影响。
<16 周妊娠的健康妇女被随机分配到两组。干预组的女性在整个孕期每周 3 天参加 60 分钟的运动方案，该方案于 2014 年 10 月至 2016 年 12 月进行。采用流行病学研究中心抑郁量表（CES-D）在研究开始时（12-16 周）、妊娠 38 周和产后 6 周测量抑郁风险。
124 名孕妇被分配到干预组（IG=70）或对照组（CG=54）。在基线时（20%对 18.5%）（χ2=0.043；p=0.836），抑郁妇女的百分比无差异。与 CG 相比，IG 在 38 孕周时（18.6%对 35.6%）（χ2=4.190；p=0.041）和产后 6 周时（14.5%对 29.8%）（χ2=3.985；p=0.046）抑郁妇女的比例较小，采用方案分析。除了在第 38 周的多重插补分析中（18.6%对 34.4%）（χ2=4.085；p=0.049），意向治疗分析未发现显著差异。
孕期运动方案可能会降低妊娠晚期和产后抑郁的发生率。
NCT02420288；结果。
