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使用实时MRI引导自适应治疗系统对一名复发性胃癌合并多种合并症患者进行挽救性放疗的病例报告

A Case Report of Salvage Radiotherapy for a Patient with Recurrent Gastric Cancer and Multiple Comorbidities Using Real-time MRI-guided Adaptive Treatment System.

作者信息

Chun Seok-Joo, Jeon Seung Hyuck, Chie Eui Kyu

机构信息

Department of Radiation Oncology, Seoul National University Hospital.

出版信息

Cureus. 2018 Apr 12;10(4):e2471. doi: 10.7759/cureus.2471.

Abstract

The stomach is one of the most deforming organs caused by respiratory motions and daily variation by food intake. Applying radiotherapy has been quite a challenge due to the high risk of missing the target as well as radiation exposure to large volumes of normal tissue. However, real-time magnetic resonance (MR)-guided radiotherapy with adaptive planning could focus the high dose radiation to the target area while minimizing neighboring normal tissue exposure and compensate for not only daily but real-time variation. Here is a case report of a patient with recurrent gastric cancer and multiple co-morbidities, unsuitable for both resection and chemotherapy, who underwent MR guided adaptive radiotherapy.

摘要

胃是受呼吸运动和每日食物摄入变化影响最易变形的器官之一。由于存在高漏靶风险以及大量正常组织受辐射暴露,实施放射治疗颇具挑战。然而,具有自适应计划的实时磁共振(MR)引导放疗能够将高剂量辐射聚焦于靶区,同时使邻近正常组织暴露最小化,不仅能补偿每日变化,还能补偿实时变化。本文报告一例复发性胃癌合并多种共病、既不适合手术切除也不适合化疗的患者接受MR引导自适应放疗的病例。

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