Chun Seok-Joo, Jeon Seung Hyuck, Chie Eui Kyu
Department of Radiation Oncology, Seoul National University Hospital.
Cureus. 2018 Apr 12;10(4):e2471. doi: 10.7759/cureus.2471.
The stomach is one of the most deforming organs caused by respiratory motions and daily variation by food intake. Applying radiotherapy has been quite a challenge due to the high risk of missing the target as well as radiation exposure to large volumes of normal tissue. However, real-time magnetic resonance (MR)-guided radiotherapy with adaptive planning could focus the high dose radiation to the target area while minimizing neighboring normal tissue exposure and compensate for not only daily but real-time variation. Here is a case report of a patient with recurrent gastric cancer and multiple co-morbidities, unsuitable for both resection and chemotherapy, who underwent MR guided adaptive radiotherapy.
胃是受呼吸运动和每日食物摄入变化影响最易变形的器官之一。由于存在高漏靶风险以及大量正常组织受辐射暴露,实施放射治疗颇具挑战。然而,具有自适应计划的实时磁共振(MR)引导放疗能够将高剂量辐射聚焦于靶区,同时使邻近正常组织暴露最小化,不仅能补偿每日变化,还能补偿实时变化。本文报告一例复发性胃癌合并多种共病、既不适合手术切除也不适合化疗的患者接受MR引导自适应放疗的病例。