Sansone Roberto, Baaken Maximilian, Horn Patrick, Schuler Dominik, Westenfeld Ralf, Amabile Nicolas, Kelm Malte, Heiss Christian
Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Duesseldorf, Germany.
Institut Mutualiste Montsouris, Paris, France.
Data Brief. 2018 May 8;19:495-500. doi: 10.1016/j.dib.2018.04.149. eCollection 2018 Aug.
Endothelial microparticles (EMPs) are markers of endothelial injury and activation. The role of EMPs in arterial hypertension is not well understood and EMPs are increased both in arterial hypertension and coronary artery disease (CAD). The data presented here show EMPs as defined by CD31/41, CD62e, and CD144 surface markers and vascular hemodynamic parameters including office and central blood pressure, heart rate, aortic augmentation index, pulse wave velocity, flow-mediated dilation, nitroglycerin-mediated dilation, brachial artery diameter, hyperemic wall shear stress, and laser Doppler perfusion of the cutaneous microcirculation of normotensives and hypertensives with and without CAD.
内皮微粒（EMPs）是内皮损伤和激活的标志物。EMPs在动脉高血压中的作用尚未完全明确，且在动脉高血压和冠状动脉疾病（CAD）中均有所增加。本文所呈现的数据显示了通过CD31/41、CD62e和CD144表面标志物定义的EMPs以及血管血流动力学参数，包括诊室血压和中心血压、心率、主动脉增强指数、脉搏波速度、血流介导的舒张功能、硝酸甘油介导的舒张功能、肱动脉直径、充血性壁切应力以及有或无CAD的高血压患者和正常血压者皮肤微循环的激光多普勒灌注。
