Department of Biomedical Engineering, Tulane University, 500 Lindy Boggs Center, New Orleans, LA 70118, United States of America.
Phys Med Biol. 2018 Jul 9;63(14):14TR01. doi: 10.1088/1361-6560/aaccd9.
The function of the placenta is challenging to characterize and as a result is understudied, despite the growing awareness of the impact of the placental environment on human health and development. Medical imaging has the potential to improve our ability to screen for diseases associated with placental insufficiency, and improve the monitoring and treatment of complex obstetric patients. This review provides an overview of clinical and preclinical imaging modalities currently available for assessing placental function, with an emphasis on emerging preclinical imaging modalities; as a group, these emerging modalities provide exceptional contrast and sensitivity for multimodal functional and molecular imaging of the placenta. Analysis of the successes and failures of medical imaging thus far provides guidance for the research community seeking to develop new imaging systems to assess placental function.
胎盘的功能难以描述，因此研究不足，尽管人们越来越意识到胎盘环境对人类健康和发育的影响。医学成像有可能提高我们筛查与胎盘功能不全相关疾病的能力，并改善对复杂产科患者的监测和治疗。本综述概述了目前用于评估胎盘功能的临床和临床前成像方式，重点介绍了新兴的临床前成像方式；作为一个整体，这些新兴方式为胎盘的多模态功能和分子成像提供了出色的对比和灵敏度。对迄今为止医学成像的成功和失败的分析为寻求开发新的成像系统来评估胎盘功能的研究团体提供了指导。
