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希腊卡瓦拉州女性自然绝经年龄与职业状况及其他流行病学因素的相关性。

Correlation of age at natural menopause with occupational status and other epidemiologic factors in women from Prefecture of Kavala, Greece.

作者信息

Koukouliata A, Nena E, Koutlaki N, Liberis V, Constantinidis T C

机构信息

Postgraduate Programme "Health and Safety in Workplace", Medical School, Democritus University of Thrace, Alexandroupolis, Greece.

Laboratory of Hygiene and Environmental Protection, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.

出版信息

Hippokratia. 2017 Jan-Mar;21(1):32-37.

Abstract

AIM

Aim of this study was to explore possible associations between the timing of natural menopause and occupational status and other determinant epidemiologic factors among women living in the Prefecture of Kavala, a region of North-East Greece.

METHODS

The sample of the study comprised of 827 naturally menopausal women, who consented to participate in this questionnaire-based interview study between 2011 and 2016. The study population was recruited from women who were hospitalized or visited the outpatient clinics of the General Hospital of Kavala and women working in the public sector services and private companies in the Prefecture of Kavala.

RESULTS

The mean age of the sample at natural menopause was 49.1 years; 12.2 % had early menopause, and 4.5 % were diagnosed with premature ovarian failure. For the majority of enrolled women (80.5 %) menopause occurred between 45-54 years, and for the rest (2.8 %) after 54 years of age. In univariate analysis, a statistically significant correlation was found between age at menopause and occupational status, year of birth, mother's age at menopause, age at menarche, and high levels of chronic stress. Multiple regression analysis revealed that occupational status, year of birth and mother's natural menopausal age could predict age at menopause.

CONCLUSION

Socioeconomic, demographic and familial variables appear to be associated with age at natural menopause in a representative sample of women in the Prefecture of Kavala, Greece. HIPPOKRATIA 2017, 21(1): 32-37.

摘要

目的

本研究旨在探讨希腊东北部卡瓦拉地区自然绝经时间与职业状况以及其他决定性流行病学因素之间的可能关联。

方法

本研究样本包括827名自然绝经女性,她们在2011年至2016年间同意参与这项基于问卷调查的访谈研究。研究人群来自在卡瓦拉综合医院住院或就诊的女性以及在卡瓦拉地区公共部门服务机构和私人公司工作的女性。

结果

样本中自然绝经的平均年龄为49.1岁;12.2%的女性为早绝经,4.5%被诊断为卵巢早衰。大多数入选女性(80.5%)在45至54岁之间绝经,其余(2.8%)在54岁以后绝经。在单因素分析中,发现绝经年龄与职业状况、出生年份、母亲绝经年龄、初潮年龄以及高水平的慢性应激之间存在统计学显著相关性。多元回归分析显示,职业状况、出生年份和母亲的自然绝经年龄可以预测绝经年龄。

结论

在希腊卡瓦拉地区的女性代表性样本中,社会经济、人口统计学和家族变量似乎与自然绝经年龄相关。《希波克拉底》2017年,21(1): 32 - 37。

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