Granados Ana María, Zuñiga Natalia, Ospina Camila, Merchancano Lina
Neuroradiology, Fundación Valle del Lili, Cali, Colombia.
Radiology department, Fundación Valle del Lili, Cali, Colombia.
Radiol Case Rep. 2018 Feb 3;13(2):347-351. doi: 10.1016/j.radcr.2018.01.004. eCollection 2018 Apr.
Extracranial glioblastoma (GB) metastasis is an uncommon entity, rarely described in the literature, representing 0.2% of cases of GB. Several theories have been proposed to explain the extracranial dissemination of GB, such as surgical interventions, ventriculoperitoneal shunt, and radiation therapy. We present a case of a 15-year old adolescent girl, with an initial diagnosis of low-grade glioma and later transformation to a high-grade glioma. In the final phase of the disease, the patient presented with distention and abdominal pain, secondary to peritoneal compromise of GB metastasis. The use of new therapies has increased survival times, leading to a rise in the probability of developing extracranial metastasis.
颅外胶质母细胞瘤（GB）转移是一种罕见的情况，文献中很少描述，占GB病例的0.2%。已经提出了几种理论来解释GB的颅外播散，如手术干预、脑室腹腔分流术和放射治疗。我们报告一例15岁青少年女性病例，最初诊断为低级别胶质瘤，后来转变为高级别胶质瘤。在疾病的最后阶段，患者因GB转移导致腹膜受累而出现腹胀和腹痛。新疗法的使用延长了生存时间，导致发生颅外转移的可能性增加。
