Department of Midwifery, College of Medicine and Health Sciences, University of Gondar, Po. Box 196, Gondar, Ethiopia.
BMC Pregnancy Childbirth. 2018 Jun 15;18(1):235. doi: 10.1186/s12884-018-1878-y.
Globally, tetanus toxoid protective dose immunization of the mothers is one of the strategies of maternal and neonatal tetanus prevention. Ethiopia has planned the national tetanus protection at birth coverage to reach 86% by the year 2015. However, there is still low coverage with less identified associated factors. Therefore; the purpose of this study was to assess tetanus toxoid protective dose immunization at last birth and associated factors among mothers who gave birth within one year prior to the study in Debretabor town, Northwest Ethiopia, 2016.
A community based cross sectional study was conducted from May 1 to June 10 / 2016. A total of 511 mothers were included in the study. Structured questionnaire and checklists were used to collect the data. Face to face interview with cross checking documented record were employed. A systematic random sampling technique was used. The data were entered in to Epinfo version 7.0 and then exported to SPSS version 20.0 for analysis. Both bivariate and multivariable logistic regression model were fitted and crude and Adjusted Odds ratio with 95% confidence interval were computed. Finally, statistically significant association of variables was determined based on Adjusted Odds ratio with its 95% confidence interval and p-value ≤0.05.
The proportion of tetanus toxoid protective dose immunization among mothers was 56.2% (95% CI: 52-60%). In the multivariable analysis; formal education (AOR = 2.09; 95%CI: 1.12, 3.90), planned last pregnancy (AOR = 6.63; 95%CI: 2.36, 18.63), four or more antenatal care visits (AOR = 5.16; 95%CI: 2.93, 11.14), timely antenatal care visit (AOR = 4.29; 95%CI: 1.94, 9.49), and perceived good quality of service (AOR = 2.20; 95% CI: 1.26, 3.84) were positively associated with tetanus toxoid protective dose immunization.
In this study, protective dose tetanus toxoid immunization is lower than the national target. Strengthening information education communication regarding tetanus and its prevention and encouraging timely initiation of and complete attendance of antenatal care is recommended.
在全球范围内，为母亲接种破伤风类毒素保护剂量疫苗是预防孕产妇和新生儿破伤风的策略之一。埃塞俄比亚计划到 2015 年将全国破伤风保护出生覆盖率提高到 86%。然而，覆盖率仍然很低，相关因素也较少。因此，本研究旨在评估 2016 年在埃塞俄比亚西北部德布雷塔博镇，在研究前一年内分娩的母亲最后一次分娩时破伤风类毒素保护剂量免疫接种情况及其相关因素。
这是一项 2016 年 5 月 1 日至 6 月 10 日进行的基于社区的横断面研究。共有 511 名母亲被纳入研究。使用结构化问卷和检查表收集数据。采用面对面访谈和交叉核对记录的方法。使用系统随机抽样技术。将数据录入到 Epinfo 版本 7.0 中，然后导出到 SPSS 版本 20.0 进行分析。同时进行了单变量和多变量逻辑回归模型拟合，并计算了 95%置信区间的粗比值比和调整比值比。最后，根据调整后的比值比及其 95%置信区间和 p 值≤0.05，确定具有统计学意义的变量关联。
母亲破伤风类毒素保护剂量免疫接种率为 56.2%（95%CI：52-60%）。在多变量分析中，正规教育（AOR=2.09；95%CI：1.12，3.90）、计划分娩（AOR=6.63；95%CI：2.36，18.63）、4 次或以上产前护理（AOR=5.16；95%CI：2.93，11.14）、及时产前护理（AOR=4.29；95%CI：1.94，9.49）和感知良好的服务质量（AOR=2.20；95%CI：1.26，3.84）与破伤风类毒素保护剂量免疫接种呈正相关。
在这项研究中，破伤风类毒素保护剂量免疫接种率低于国家目标。建议加强关于破伤风及其预防的信息、教育和沟通，并鼓励及时开始和完成产前护理。
