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在过去 12 个月内在埃塞俄比亚东部索马里州埃勒里地区分娩的母亲中,破伤风类毒素疫苗接种率及相关因素。

Tetanus Toxoid Vaccination Uptake and Associated Factors among Mothers Who Gave Birth in the Last 12 Months in Errer District, Somali Regional State, Eastern Ethiopia.

机构信息

Department of Public Health, College of Medicine and Health Science, Adigrat University, Adigrat, Ethiopia.

Departments of Midwifery, College of Medicine and Health Science, Adigrat University, Adigrat, Ethiopia.

出版信息

Biomed Res Int. 2020 May 7;2020:4023031. doi: 10.1155/2020/4023031. eCollection 2020.

DOI:10.1155/2020/4023031
PMID:32461983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7231084/
Abstract

BACKGROUND

Maternal tetanus is defined as tetanus acquired during pregnancy or within 6 weeks after the end of conception. As tetanus is a vaccine-preventable disease, immunization of pregnant mothers with a TT (tetanus toxoid) dose is one of the most effective ways to protect against the disease. Some studies showed that 94% of neonatal mortality reduction could be achieved through immunization of pregnant and childbearing-age mothers with at least two doses of TT vaccination.

OBJECTIVE

To assess the uptake of tetanus toxoid vaccine and associated factors among mothers who gave birth in the last 12 months in Errer district, Somali Regional State, Eastern Ethiopia, 2017.

METHODS AND MATERIALS

A community-based cross-sectional study design was implemented to study 440 mothers who gave birth in the last 12 months. Participants were selected using the strata and systematic sampling technique after conducting a preliminary survey. Data were collected through a face-to-face interviewer-administered questionnaire. The collected data was entered into EpiData version 3.02 and then exported to Statistical Package for the Social Sciences (SPSS) version 20. Bivariate and multivariate logistic regressions were carried out to see the association between variables at < 0.05 and 95% confidence interval. Finally, the information was presented by using frequencies, summary measures, and tables.

RESULT

The overall tetanus vaccination uptake (≥TT2) doses was found to be 51.8%, 95% CI (47.7%, 56.4%). The total number of mothers who complete the five TT doses was 31 (14.8%). Urban residence [AOR = 6.1, 95% CI: (2.33, 10.43)], multiparity [AOR = 2.3, 95% CI: (1.7, 6.4)], and traveling less than 30 minutes from the home to a health facility [AOR = 4.6, 95% CI: (1.34, 6.72)] were some the factors that were significantly associated with tetanus toxoid vaccination uptake. . Although TT immunization is a scientifically proven mechanism to protect against maternal and neonatal tetanus, only half of the district mothers received ≥TT2 doses. Besides, our study revealed that the low vaccine uptake is attributed to long distance travel to reach a health facility, maternal illiteracy, and pastoralist lifestyle of mothers in the district. Thus, the regional stakeholders are required to scale up efforts on mother's awareness creation towards the importance of the vaccine through health education and to arrange outreach TT vaccination campaigns in distant pastoralist communities within the region.

摘要

背景

母体破伤风是指在怀孕期间或受孕结束后 6 周内发生的破伤风。由于破伤风是一种可通过疫苗预防的疾病,因此为孕妇接种破伤风类毒素(TT)是预防该病的最有效方法之一。一些研究表明,通过为孕妇和育龄妇女接种至少两剂 TT 疫苗,可使新生儿死亡率降低 94%。

目的

评估 2017 年在埃塞俄比亚东部索马里州埃勒尔区最近 12 个月分娩的母亲接种破伤风类毒素疫苗的情况及其相关因素。

方法和材料

采用社区为基础的横断面研究设计,对最近 12 个月分娩的 440 名母亲进行研究。在进行初步调查后,采用分层和系统抽样技术选择参与者。通过面对面访谈员管理的问卷收集数据。收集的数据输入 EpiData 版本 3.02,然后导出到统计软件包社会科学版(SPSS)版本 20。进行了单变量和多变量逻辑回归分析,以了解变量之间的关联,置信区间为 < 0.05。最后,采用频率、汇总指标和表格来呈现信息。

结果

破伤风类毒素疫苗接种(≥TT2)总剂量发现为 51.8%,95%CI(47.7%,56.4%)。完成 5 剂 TT 疫苗接种的母亲总人数为 31 人(14.8%)。城市居住[比值比(AOR)=6.1,95%置信区间(CI):(2.33,10.43)]、多胎次[AOR=2.3,95%CI:(1.7,6.4)]和居住地距卫生机构少于 30 分钟[AOR=4.6,95%CI:(1.34,6.72)]是与破伤风类毒素疫苗接种相关的一些因素。虽然 TT 免疫是预防母体和新生儿破伤风的一种经过科学验证的机制,但只有一半的地区母亲接受了≥TT2 剂量。此外,我们的研究表明,疫苗接种率低归因于前往卫生机构的长途旅行、母亲文盲和该地区母亲的牧民生活方式。因此,需要加强区域利益攸关方的努力,通过健康教育提高母亲对疫苗重要性的认识,并在该地区偏远的牧民社区开展扩大范围的 TT 疫苗接种运动。

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